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Abstract #149452
Audio (mp3) recordingRichard A. Crosby, PhD1, Ralph DiClemente, PhD2, Gina Wingood, MPH ScD2, and Laura F. Salazar, PhD2. (1) College of Public Health, University of Kentucky, 121 Washington Ave, Suite 111, Lexington, KY 40536-0003, 859-257-5678, crosby@uky.edu, (2) Rollins School of Public Health and Center for AIDS Research, Emory Univeristy, 1518 Clifton Rd NE, Room 554, Atlanta, GA 30322
Differences Between African American Adolescent Females With and Without Human Papillomavirus Infection
Objectives: An important policy question is whether high-risk populations of adolescent females can be identified and prioritized for HPV immunization. We investigated differences in sexual risk behaviors between 133 African American adolescent females testing positive for one or more of 18 HPV subtypes and 164 testing negative for each subtype. Methods: Data collection included a) an audio-computer assisted self-interview and a self-collected vaginal swab for nucleic acid amplification testing of Trichomonas vaginalis, Chlamydia trachomatis, and Neisseria gonorrhoeae. The Gen-Probe Aptima Combo 2 assay was used to detect 18 subtypes of human Papillomavirus. Results: Groups did not differ by prevalence of other STDs (P=.31). Moreover, they did not differ by whether they had sex with older (by 5 or more years) male partners (P=.90), whether the currently had sex with casual partners (P=.78), whether they had any unprotected vaginal sex in the past 60 days (P=.92), or the frequency of engaging in vaginal sex in the past 60 days (P=.56). Differences were not found regarding number of male sex partners in the past 60 days (P=.69) or the number of partners accumulated over the lifetime (P=.10). However, age was significantly different with those testing positive being younger (mean=17.7 years) than those testing negative (mean=18.7 years) (P=.03). Conclusion: The weight of evidence suggests that among African American adolescent females it may not be possible to identify those with elevated risk of HPV acquisition. Thus, vaccination of African American adolescent females, regardless of risk indicators, may be the most efficacious public health strategy.
Learning Objectives:
- 1.Describe the implications of the study for HPV immunization practices of African American adolescent females.
- 2.Identify potential reasons why differences between those having and not having HPV were found.
Presenting author's disclosure statement:
Any relevant financial relationships? No
Any institutionally-contracted trials related to this submission?
I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.
The 135th APHA Annual Meeting & Exposition (November 3-7, 2007) of APHA