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APHA Scientific Session and Event Listing
3364.0: Monday, November 05, 2007 - 2:30 PM

Abstract #149515

Geocoding and selection bias in public health research using geographic information systems

M. Norman Oliver, MD1, Kevin A. Matthews, MS2, Mir S. Siadaty, MD, MS3, Fern R. Hauck, MD, MS1, and Linda Pickle, PhD4. (1) Department of Family Medicine, University of Virginia School of Medicine, Box 800729, Charlottesville, VA 22908, 434-982-1754, noliver@virginia.edu, (2) Department of Family Medicine, University of Virginia, P.O. Box 800729, Charlottesville, VA 22908, (3) Department of Public Health Sciences, University of Virginia, P.O. box 800717, Charlottesville, VA 22908, (4) Surveillance Research Program, National Cancer Institute, 6116 Executive Blvd. Suite 504, Bethesda, MD 20892

Objective: Describe selection bias in GIS analyses with unrepresentative data owing to missing geocodes. Design: Spatial analysis of prostate cancer incidence among whites and African Americans in Virginia, 1990-1999, using the Virginia Cancer Registry. Outcome measures: Statistical tests for clustering were performed and mapped. The patterns of missing census tract identifiers for the cases were examined by general linear regression models and stratified by rural status. Results: All cases in the VCR are located in counties, and 26,338 (74%) of these cases were successfully geocoded to census tracts. Statistical testing for global clustering was highly significant for the entire study period and for 1990-94 and 1995-99 separately. For each time period, however, cluster patterns appeared markedly different, depending upon whether one used the cases located in the county or those geocoded to the census tract. Multivariate regression analysis showed that, in the most rural counties (where the missing data were concentrated), the percent of a county's population over age 64 and with less than a high school education were both independently associated with a higher percent of missing geocodes (p = 0.016 and p = 0.003, respectively). Discussion: We found statistically significant pattern differences resulting from spatially non-random differences in geocoding completeness across Virginia. Appropriate interpretation of maps, therefore, requires an understanding of this phenomenon, which we call “cartographic confounding.”

Learning Objectives:

Keywords: Geographic Information Systems, Geocoding

Presenting author's disclosure statement:

Any relevant financial relationships? No
Any institutionally-contracted trials related to this submission?

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.

Applications of Statistical Methods to GIS-Based Analyses of Public Health Problems

The 135th APHA Annual Meeting & Exposition (November 3-7, 2007) of APHA