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Abstract #152564

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Raouf Arafat, MD, MPH¹, Adebowale Awosika-Olumo, MD, MS, MPH², James Gomez³, Marcia Wolverton, MPH⁴, and Lydwina Anderson³. (1) Houston Department of Health and Human Services, 8000 N Stadium Dr 8th floor, Houston, TX 77054, 713-794-9185, Raouf.Arafat@cityofhouston.net, (2) Bureau of Epidemiology, City of Houston, Department of Health and Human Services, 8000 N. Stadium Drive, 4th Floor, Houston, TX 77054, (3) Houston Department of Health and Human Services, Bureau of Epidemiology, 8000 N. Satdium Drive, Houston, TX 77054, (4) Bureau of Epidemiology, Houston Department of Health and Human Services, 8000 N Stadium Dr 4th floor, Houston, TX 77054

OBJECTIVE: To examine the survival profile of human immunodeficiency virus (HIV) infection of U.S. born Hispanics in comparison to Foreign-born Hispanics with respect to basic demographic characteristics in Houston, and factors associated with early mortality.

Method: We analyzed from the Adult and Adolescent Spectrum HIV Diseases Project (1990-2001) of a cohort of 876 patients of Hispanic origin. The statistical analysis was performed using Kaplan-Meier, Log Rank test, and Cox proportional regression analysis.

RESULTS: By Kaplan Meier analysis early death was associated with U.S. Born Hispanics (log rank test p = .0015). A Cox proportional regression analysis, in which gender, age, and social risk factors were introduced as controls, drug/alcohol abuse were shown to be predictors to a less favorable survival experience (Hazard Ratio [HR] = 1.3, 95% confidence interval [CI] : 1.1 – 1.6). In addition, from 1990 to 1995, higher increases in the occurrences of opportunistic infections were observed among U.S. born compared to Foreign-born Hispanics.

CONCLUSION: The findings of this study lend support to other investigations which have suggested that factors such as acculturation, coupled with a loss of support systems, may explain a negative survival outcome for U.S. born Hispanics in comparison to those that are foreign-born.

Learning Objectives:

• To examine the survival profile of human immunodeficiency virus (HIV) infection of U.S. and foreign born Hispanics.
• To compare U.S. and Foreign-born Hispanics with respect to basic demographic characteristics in Houston, and factors associated with early mortality

Keywords: Mortality, HIV/AIDS

Presenting author's disclosure statement:

Any relevant financial relationships? No
Any institutionally-contracted trials related to this submission?

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.

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