Back to Annual Meeting

Back to Annual Meeting

Abstract #153690

Pangaja Paramsothy, MPH¹, Denise J. Jamieson, MD, MPH², Maura K. Whiteman, PhD², Susan F. Meikle, MD MSPH³, Athena P. Kourtis, MD, MPH, PhD², and Samuel F. Posner, PhD⁴. (1) CONRAD Program, 2971 Flowers Rd S. Suite 280, Atlanta, GA 30341, 770-986-7753, pfp5@cdc.gov, (2) Division of Reproductive Health, Centers for Disease Control and Prevention, 4770 Buford Highway, MS K34, Atlanta, GA 30341, (3) Office of Research on Women's Health/ Office of the Director, National Institutes of Health, 6707 Democracy Blvd, Suite 400, MSC 5484, Bethesda, MD 20892-5484, (4) Division of Reproductive Helth, Centers for Disease Control and Prevention, 4770 Buford Highway, MS K20, Atlanta, GA 30341

Background: Although hysterectomy is one of the most common surgical procedures in women, few studies have examined hysterectomy in HIV-infected women. The objective of the current study was to compare hospitalization characteristics and indications for hysterectomy in HIV-infected women and HIV-uninfected women. Methods: We utilized data from the Nationwide Inpatient Sample (NIS) of the Healthcare Cost and Utilization Project (HCUP), 1994-2004. International Classification of Diseases 9th revision Clinical Modification (ICD-9-CM) codes were used to identify HIV infection, hysterectomy, indications for hysterectomy, comorbities, and complications. Standard methods for analyzing weighted survey data were employed using SAS- callable SUDAAN. Results: This analysis included 7,823 HIV-infected women and 6,454,963 HIV-uninfected women who underwent a hysterectomy. On average, HIV-infected women underwent hysterectomy at a younger age than non-infected women (39.7 years vs. 47.0 years, p<.001) and had a longer length of hospital stay (4.6 days vs. 3.1 days, p<.001). A greater percentage of HIV-infected women than uninfected women had a surgical or post-operative complication during hysterectomy hospitalization (34.8% vs. 25.8%, p<.001). Adjusting for age and year, HIV-infected women were more likely to have an indication of cervical cancer (OR=2.6, 95% CI 1.9-3.6), cervical intraepithelial neoplasia III (OR=8.0, 95% CI 6.9-9.2), cervical intraepithelial neoplasia I-II (OR=5.3, 95% CI 4.6-6.2), and pelvic inflammatory disease (OR=1.4, 95% CI 1.2-1.5). Discussion: HIV-infected women undergoing hysterectomy were younger, and more likely to have different indications and complications than HIV-uninfected women. Further research is need to identify the reason for these differences.

Learning Objectives:

• Identify differences in hysterectomy indications among HIV-infected and HIV-uninfected women.
• Describe differences in hysterectomy hospitalizations among HIV-infected and HIV-uninfected women.
• Discuss the possible impact on gynecologic care of HIV-infected women

Keywords: Women and HIV/AIDS, Reproductive Health

Presenting author's disclosure statement:

Any relevant financial relationships? No
Any institutionally-contracted trials related to this submission?

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.