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APHA Scientific Session and Event Listing
4024.0: Tuesday, November 06, 2007 - 9:20 AM

Abstract #160551

Factors associated with diabetes and impaired fasting glucose in individuals with a family history

Christina M. Lefante, MPH1, L. Joseph Su, PhD, MPH1, Eric Ravussin, PhD2, S. Michal Jazwinski, PhD3, Katie E. Cherry, PhD4, David A. Welsh, MD5, Jennifer C. Rood, PhD, DABCC, FACB2, and Crystal Traylor, WHNP2. (1) Department of Epidemiology, School of Public Health, Louisiana State University Health Sciences Center, 2021 Lakeshore Drive, Suite 210, New Orleans, LA 70122, 504-568-3119, clefan@lsuhsc.edu, (2) Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, (3) Department of Biochemistry & Molecular Biology, Louisiana State University Health Sciences Center, 1901 Perdido St., Box P7-2, New Orleans, LA 70112, (4) Department of Psychology, Lousiana State University, 236 Audubon Hall, Baton Rouge, LA 70803-5501, (5) Department of Pulmonary & Critical Care Medicine, Lousiana State University Health Sciences Center, 1901 Perdido St., Suite 3205, New Orleans, LA 70112

According to the NHANES (1999-2000) survey, an estimated 16.7 million U.S. adults aged 20 years or greater had diabetes while an estimated 12.3 million had impaired fasting glucose (IFG)1, a potential indicator of progression to type 2 diabetes2. The large number of U.S. adults with and predisposed to diabetes demonstrates the need for earlier detection. This study assessed characteristics of undiagnosed diabetes and pre-diabetes in the Louisiana Healthy Aging Study, a multidisciplinary population-based study that examines the determinants of healthy aging. Overall, 619 individuals aged 20 to 102 were randomly sampled and recruited using Medicare Beneficiary Enrollment and Louisiana Voters registration files. Self-reported diabetes and family history of a first degree relative with diabetes was ascertained. Fasting blood glucose was measured and participants were characterized pre-diabetic or diabetic based on American Diabetes Association guidelines. Chi-square and logistic regression were used to assess the association between fasting glucose concentration and family history by self-reported diabetes status. Among individuals not reporting a diagnosis of diabetes, 8%(n=15) with a family history had diabetes while 39.6%(n=74) had pre-diabetes. Family History (OR:1.49 CI:1.05-2.09), body mass index (OR:2.08 CI:1.45-2.97), male gender (OR:2.37 CI:1.69-3.33), and age >65 (OR:2.03 CI:1.44-2.88) were strong predictors of having diabetes or IFG after adjusting for confounding factors. These findings suggest that a significant proportion of individuals in this study at risk for diabetes are not receiving proper screening. This research was supported by the Louisiana Board of Regents Millennium Trust Health Excellence Fund [HEF(2001-06)-02] and National Institute on Aging [P01AG022064].

Learning Objectives:

Keywords: Diabetes, Risk Factors

Presenting author's disclosure statement:

Any relevant financial relationships? No
Any institutionally-contracted trials related to this submission?

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.

Diabetes Epidemiology

The 135th APHA Annual Meeting & Exposition (November 3-7, 2007) of APHA