226744 Herpes Simplex Virus Type 1 and Type 2 Seroprevalence in Los Angeles County: Findings from the National Health and Nutrition Examination Survey, 1999-2004 (National Center for Health Statistics, Hyattsville, MD 20782)

Monday, November 8, 2010 : 3:10 PM - 3:30 PM

Veena G. Goud, ScM , National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD
Deanna Kruszon-Moran, ScM , National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD
Kathryn S. Porter, MD, MS , National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD
Geraldine McQuillan, PhD , National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD
Robert Kim-Farley, MD, MPH , Communicable Disease Control and Prevention, Department of Public Health County of Los Angeles, Los Angeles, CA
Background: Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are common infections worldwide. HSV-2, in contrast to HSV-1, is usually sexually transmitted. In many localities prevalence estimates for HSV-1 and HSV-2 are not available. This study presents prevalence estimates for Los Angeles County (LAC) among participants aged 14-49 years.

Methods: Data from the 1999-2004 National Health and Nutrition Examination Survey (NHANES), a cross-sectional, nationally representative survey of the US civilian non-institutionalized population, were used in the analysis. Sample weights were recalculated for participants examined in Los Angles County (LAC) using population totals provided by the local Department of Public Health.

Results: Seroprevalence of HSV-1 in LAC was 64.6% (95% CI, 57.4%-71.4%). Age and race adjusted estimates were 50.6% (95% CI, 40.5%-60.7%) for LAC compared with 57.8% (95% CI, 56.1 %-59.5 %) for the US. Seroprevalence of HSV-2 in LAC was 21.9% (95% CI, 14.3 %-31.3 %). Age and race adjusted estimates were 24.4% (95% CI, 14.2 %-37.3%) for LAC compared with 17.3% (95% CI, 16.3 %-18.3 %) for the US. Seroprevalence for HSV-1 and HSV-2 was consistently higher among older participants (age 30-49 years), females, and those below poverty for both the US and LAC although statistical significance (p<0.05) was not always reached within the LAC sample.

Conclusion: Almost two-thirds of LAC residents were HSV-1 seropositive and one-fifth HSV-2 seropositive. No significant differences were found in either HSV-1 and HSV-2 seropositivity when comparing the LAC sample to the US and trends by age, gender and poverty were similar.

Learning Areas:
Epidemiology

Learning Objectives:
Demonstrate the use of National Health and Nutrition Examination Survey (NHANES) data at the local level.

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I oversaw the analysis submitted.
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.

Back to: 3350.0: Statistical Applications of Survey Methods