3212.0: Monday, October 22, 2001 - Board 3

Abstract #22853

Clinical assessment of quality of life among schizophrenia patients with deficit syndrome

Patricia Russo, PhD, MSW, RN, Director, Outcomes Research and Econometrics, The MEDSTAT Group, 4301 Connecticut Avenue NW, Suite 330, Washington, DC 20008, 202 719-7826, pat.russo@medstat.com and Brian Kirkpatrick, MD, Maryland Psychiatric Research Center, University of Maryland, P.O. Box 21247, Baltimore, MD 21228.

Objective: To determine whether persons with deficit syndrome exhibit lower quality of life than do their counterparts. Methods: Baseline QLS data (n=781; mean=56) from the U.S. Schizophrenia Care and Assessment Program (SCAP) were used and were modeled as a linear function of covariates, including demographic, clinical, medication adherence, and site variables. Presence of deficit syndrome was assigned based on proxy methods (Kirkpatrick B., et al., 1993). Results: Modeling revealed that deficit syndrome had a negative impact of 4.7 points (p<.001) on quality of life score (range 0-120). Those having higher hallucinations/delusions scores (p<.001) exhibited lower QLS scores and those with higher functioning scores (GAF; p<.001) exhibited higher QLS scores. The presence of insurance other than Medicare or Medicaid (as compared to no insurance) revealed a positive relationship. A significant (negative) effect was observed on one site variable. Weak evidence was obtained (p=.0587) indicating a positive association between higher education level and QLS score. Conclusions: Findings suggest that persons with deficit syndrome experience lower quality of life than those who are non-deficit. The result is expected given the use of clinical assessment of quality of life and is contrary to the expectation of higher self-reported quality of life for persons with deficit. The impact of deficit syndrome is at least five times greater than that of hallucinations/delusions. The interpretation of significance on the insurance and site variables is less clear and may suggest that the observed variation is a result of an unobserved mediating process, such as selection or differential access.

Learning Objectives: Attendees will be able to identify key factors in the determination of QoL;

Keywords: Quality of Life, Mental Health

Presenting author's disclosure statement:
Organization/institution whose products or services will be discussed: None
I do not have any significant financial interest/arrangement or affiliation with any organization/institution whose products or services are being discussed in this session.

The 129th Annual Meeting of APHA