3237.0: Monday, October 22, 2001 - 4:45 PM

Abstract #27901

Post-Surgical Assessment of Psychological Distress in Breast Cancer

Erica S. Breslau, MPH, PhD1, Barbara A Curbow, PhD1, James R Zabora, ScD2, and Giovanni Parmigiani, PhD2. (1) Faculty of Social and Behavioral Sciences, Department of Health Policy and Management, Johns Hopkins School of Public Health, 624 N. Broadway Street, Room 745, Baltimore, MD 21205, , ebreslau@jhsph.edu, (2) Johns Hopkins School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287

PURPOSE: Objectives of the current study were to evaluate the frequency of psychological distress in post-surgical women with breast cancer, and to identify sociodemographic and biomedical variables assocaited with distress. METHODS: Two hundred and sixty-six post-surgical women with breast cancer attending an ambulatory outpatient clinic completed a self-report instrument, the Brief Symptom Inventory. Demographic, pathological and histological data on the breast tumor were obtained from a hospital cancer registry. RESULTS: More than a third (31%) were distressed. For individual psychological data, 26% reported obsessive-compulsive thoughts, 23% were anxious, 21% indicated somatic symptoms, and 18% reported psychotic thoughts. Logistic regression analysis revealed non-whites were more likely to report higher interpersonal sensitivity (OR=2.80, 95%CI=1.08, 4.80), higher psychoticism (OR=1.98, 95%CI=0.94, 4.08), and higher paranoid ideation (OR=2.59, 95%CI=0.11, 5.74) than white counterparts, but were less likely to report hostility (OR=0.35, 95%CI=0.11, 1.15). By contrast, those older (>50 years) were less likely to be depressed (OR=0.45, 95%CI=0.19, 1.06) than younger women. Compared to early stage (Stage IIB), those with late stage (Stage IV) breast cancer were more likely to be depressed (OR=2.40, 95%CI=0.88, 6.02), paranoid (OR=2.10, 95%CI=0.96, 4.67), and psychotic (OR=3.30, 95%CI=1.41, 7.88). CONCLUSIONS: Findings suggest that oncologists and health care workers should be aware that psychological distress is ubiquitious in a subset of breast cancer patients in the period following surgery. Clarification of the nature of this group's psycholgoical well-being warrants further research and clincal attention.

Learning Objectives: N/A

Keywords: Breast Cancer, Psychosocial Issues of Cancer

Presenting author's disclosure statement:
Organization/institution whose products or services will be discussed: None
I do not have any significant financial interest/arrangement or affiliation with any organization/institution whose products or services are being discussed in this session.

The 129th Annual Meeting of APHA