The Cape Cod Breast Cancer and Environment Study targets three overlapping sets of compounds hypothesized to affect breast cancer risk: pesticides, endocrine disruptors, and animal mammary carcinogens. Because information about indoor concentrations and human exposures for many of these compounds is very limited, new methods and results of the Cape Study are of broad interest. For example, the Cape Study reported some of the first measurements in indoor air for phthalates, which are endocrine disruptors found in many plastics. Phthalates are of interest because of their possible effects on multiple health end points, such as asthma and premature puberty, as well as on breast cancer. The Cape Cod Study includes testing of urine samples and household air and dust in 120 homes in conjunction with a questionnaire about recent use of products that may be sources of the target compounds. Results from the first 30 homes showed that phthalates are abundant in household dust and air at levels that are an order of magnitude higher than other contaminants, such as polycyclic aromatic hydrocarbons (PAHs). Correspondence between household air and dust, urine samples from women living in the sampled homes, and urine samples collected from a nationally representative sample of women will be discussed. Results indicate widespread exposure to target compunds in indoor environments and demonstrate the efficacy of new exposure assessment methods. See www. Silent Spring.org
Learning Objectives: 1. Describe methods for assessing exposures to indoor pollutants 2. Describe indoor levels of certain pesticides, endocrine disruptors, and animal mammary carcinogens 3. Understand correspondence of air, dust, and urine samples
Keywords: Pesticides, Indoor Environment
Presenting author's disclosure statement:
Organization/institution whose products or services will be discussed: None
I do not have any significant financial interest/arrangement or affiliation with any organization/institution whose products or services are being discussed in this session.