The 130th Annual Meeting of APHA

3287.0: Monday, November 11, 2002 - Board 9

Abstract #36873

Substance use trajectories and affective states among subjects with differential family alcohol abuse and depression diagnoses

Valerie Johnson, PhD, Center of Alcohol Studies, Rutgers University, 607 Allison Rd., Piscataway, NJ 08854, 732-445-2424,

There is evidence linking both substance use and negative affective states among probands with familial alcoholism. However, the methods used to classify familial risk have varied across studies. This longitudinal, prospective study examined the alcohol and marijuana use trajectories (over a 20-year time span), as well as affective (including arousal needs, negative affect and depression) differences between young adults from families classified by four different methods as to the presence or absence of a lifetime diagnosis of alcohol use disorder and depression. Data were obtained from a community sample who participated in the Rutgers Health and Human Development Study. These probands were a non-clinical sample who were originally tested in 1979-81 at the age of 12, 15, or 18 (T1). Subjects were assessed using standardized inventories, self-report questionnaires and individual interviews three (T2), six (T3), and 13 (T4) years later (N=1200). The Family History-Research Diagnostic Criteria was administered to the probands and used to determine lifetime diagnoses of alcohol use disorders (FHA+) and depression (FHD+) in each first degree family member. Families were then grouped using four alternative classifications of parental and sibling alcohol and depression diagnoses. Results confirmed family group differences in negative affect, lifetime alcohol and marijuana use, and time 4 depression, but no differences in arousal needs. The method by which a subject was categorized into a family group resulted in somewhat subtle differences in the variation of the outcomes of interest.

Learning Objectives: Information acquired