The 130th Annual Meeting of APHA

Abstract #41894

F. J. López-Antuñano, National Institute of Public Health, Avenida Universidad No. 655, Cuernavaca, Morelos, Mexico, 0173 175391, jcampuzano@correo.insp.mx and L. M. Sanchez-Zamorano, Department of tobacco exposition research, National Institute of Public Health, Av. Universidad 655, Col. Sta. Maria Ahuacatitlan, CP 62508, Cuernavaca, Mor., MEXICO, Cuernavaca, Mor., 62508, Mexico.

Learning Objectives:

Introduction. Coronary heart disease (CHD) is the main cause of mortality in Mexico. Cigarette smoking is a well-known risk factor for this pathology and other diseases, inability and preventable premature death. It's prevalence in our country is higher than 27% and it's unknown its contribution in CHD. Objective. To evaluate the impact due to cigarette smoking in coronary heart disease and also to propose a simple and efficient standard methodology in order to estimate the attributable fraction. Method. We carried out a case-control study in the Regional Hospital of Mexican Institute of Social Security in Morelos State, from May to June-200
• The cases were 80 prevalent and incident patients with CHD. One hundred sixty outpatients were selected randomly matching by sex and age. The attributable fraction was obtained through odds ratio summarized, variance and confidence intervals for matching designs with more than one control for each case. Results. Prevalence of cigarette smoking previous to coronary event was 80% compared to 62.1% of controls prevalence. Mantel & Haenszel odds ratio showed a positive association to cigarette smoking with CHD (OR, 6.7; 95%CI, 3.2-13.8). Attributable fraction among exposed individuals was 85% (95%CI, 74-9
• while population attributable fraction was 56% (95%CI, 45-66), in men were 65% (95%CI, 53 -7
• and women were 31% (95%CI 14 - 47). Conclusions. Smoking impact on CHD is high. The used method allow us evaluate efficiently the attributable fraction and weighted a mortality participation due to this pathology and may be to detect changes derived of the anti-tobacco programs.

Keywords: Epidemiology, Hispanic

Related Web page: www.insp.mx

Presenting author's disclosure statement:
Organization/institution whose products or services will be discussed: The information of this study is necessary to determinate in the future, the specific cost of the Coronary Heart Disease doubt to tobacco consuption.
I do not have any significant financial interest/arrangement or affiliation with any organization/institution whose products or services are being discussed in this session.