The 130th Annual Meeting of APHA

Abstract #42492

Julio Cesar Campuzano¹, Francisco J. Lopez¹, Eduardo Cesar Lazcano¹, Mauricio Hernandez¹, and Jorge Salmerón². (1) Centro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública, Avenida Universidad No. 655, Cuernavaca, Mexico, 0173 175391, jcampuz@correo.insp.mx, (2) Unidad de Investigación Epidemiológica y en Servicios de Salud, Instituto Mexicano del Seguro Social, Avenida Universidad No. 655, Cuernavaca, Morelos, Mexico

Objective: To describe salivary cotinine levels and their relationship to cigarettes smoked per day and other smoking behavior variables. Materials and Methods. Using a purposive sampling strategy based on the number of cigarettes/day, we recruited 1,222 smokers from Mexico City and from the State of Morelos, Mexico in 1999. Information regarding tobacco smoking behavior, and other factors known to modify nicotine metabolism, were obtained using a standardized questionnaire in a face-to-face interview. Saliva cotinine was measured by capillary gas chromatography with nitrogen-phosphorous detection. We used Generalized Additive Models to describe the relationship between saliva cotinine levels and variables of interest. Results: The mean age of the population was 39,7 years (SD 15,6) with a cotinine mean level of 194,7 ng/dL (SD 134,8 ng/dL, and range from 10,1 to 767). Participants referred a mean of 15,5 cigarettes/day (SD 11,3 cigarettes/day). Saliva cotinine and cigarettes/day were positively related, however the association was not linear. After adjusting for cigarettes/day, significant predictors of cotinine levels includes: age, body mass-index, Type of cigarette, manufacture company and smoking behavior variables.

Learning Objectives:

• See individual abstracts.

Keywords: Tobacco,

Presenting author's disclosure statement:
I do not have any significant financial interest/arrangement or affiliation with any organization/institution whose products or services are being discussed in this session.