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The 130th Annual Meeting of APHA |
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The 130th Annual Meeting of APHA |
Michael Berry, MPH1, Jerald Fagliano, MPH, PhD1, Jonathan Savrin, MSPH1, Barbara Goun, MPH, PhD1, Patricia Haltmeier1, James Blando, PhD, MS1, Morris Maslia2, Panos Georgopoulos, PhD3, and Paul J. Lioy, PhD4. (1) Consumer and Environmental Health Services, NJ Department of Health and Senior Services, PO Box 369, Trenton, NJ 08625, 609-588-3120, michael.berry@doh.state.nj.us, (2) Agency for Toxic Substances and Disease Registry, Executive Park MS-E32, 1600 Clifton Road, Atlanta, GA 30333, (3) Environmental and Occupational Health Sciences Institute, 170 Frelinghuysen Road, Piscataway, NJ 08854, (4) Associate Director of EOHSI and Director, Exposure Measurement and Assessment Division, University of Medicine and Dentistry of New Jersey, 170 Frelinghuysen Road, Piscataway, NJ 08854
An important challenge in an epidemiologic study of a community with elevated childhood cancer is the accurate assessment of historic exposure. The primary environmental exposures of interest in this study included contaminated water from two public water supply well fields,and ambient air emissions from a major chemical manufacturing facility in the community. Residential histories for each study subject (40 cases and 159 controls) were collected by structured interview for the period one year prior to birth to the month of diagnosis. In order to develop prenatal and postnatal exposure indices, monthly computer modeling was conducted to estimate the flow of water within the community water distribution system and the dispersion of air pollutants from the manufacturing facility. Monthly estimates of the percent of water from each of the community’s ten well fields and relative ambient air pollutant concentrations (gases and particulates) from the industrial facility were calculated for each of more than 700 study subject residences over a 35 year period, 1962-1996. Average prenatal and postnatal exposure indices were derived for each study subject using the monthly estimates for each residence the child (or mother) lived in during the study time period.
Learning Objectives:
Keywords: Environmental Exposures, Epidemiology
Presenting author's disclosure statement:
I do not have any significant financial interest/arrangement or affiliation with any organization/institution whose products or services are being discussed in this session.