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The 130th Annual Meeting of APHA |
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The 130th Annual Meeting of APHA |
4120.0: Tuesday, November 12, 2002: 12:30 PM-2:00 PM | |||
Oral | |||
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| Systemic lupus erythematosus is an inflammatory connective tissue disease that preferentially afflicts African-American women. Predisposition to lupus is inherited as a complex genetic trait that is modulated by multiple genes. Evidence is emerging that implicates environmental exposure to organic solvents in predisposition to lupus and related conditions. Thus, residing in communities suffering environmental pollution may confront genetic and environmental risks for lupus. Eradication of hazardous waste exposures is likely to proceed more rapidly than the development of biologic treatment such as gene therapies, and may prevent lupus in populations at high risk to develop this disease. There are many challenges to the investigation of how environmental exposures combine with the inherited tendencies in high risk groups to trigger lupus. The research study design must be developed with community participation to ensure culturally relevant and sensitive research tools and to provide a forum for the articulation of a community’s concern about research | |||
| Learning Objectives: 1. The participant will be able to list gender and ethnic risks associated with systemic lupus erethryametosus (SLE), as well as symptoms of this complex autoimmune disorder. 2. The participant will be able to discuss anecdotal evidence linking SLE incidence in environmentally overburdened communities with specific chemical exposures. 3. The participant will be able to recognize the utility of community-based participatory research (CBPR) approaches in the conduct of lupus screening, genetic screening, exposure assessments and etiological studies. | |||
| See individual abstracts for presenting author's disclosure statement and author's information. | |||
| Frederick L Tyson, PhD Marybeth Smuts, PhD Paul Locke, DrPH, JD | |||
| Frederick L Tyson, PhD | |||
| Community-based participatory research approaches to link chemical exposures to systemic lupus erythematosus (SLE) etiology Frederick L Tyson, PhD | |||
| Community-based participatory research: Strategies for the study of gene-environment interactions in African-American communities Patricia A Fraser, MD | |||
| Community-based research of an autoimmune disease cluster in Buffalo, New York John E Vena, PhD, Alison Howe, Ausar Africa, Akua Assata, Peter Rogerson, Julian J Ambrus, PhD | |||
| Withdrawn -- Investigation of systemic lupus in Nogales, Arizona Cecilia Rosales, MD, MS, Luis Ortega, MD, Lina Balluz, ScD, MPH | |||
| Potential linkage of organchlorine pesticide exposure and systemic lupus erythematosus in Lake Apopka farmworkers Stephen M Roberts, PhD, Eric Sobel, MD, Joel Schiffenbauer, MD, Joan Flocks, JD, Liz Buckley | |||
| Organized by: | Environment | ||
| Endorsed by: | Asian Pacific Islander Caucus of APHA; Epidemiology | ||