The 131st Annual Meeting (November 15-19, 2003) of APHA

The 131st Annual Meeting (November 15-19, 2003) of APHA

4241.0: Tuesday, November 18, 2003 - 5:30 PM

Abstract #57307

Hepatitis A and hepatitis B virus prevalence and history of vaccination among younger injection drug users in Los Angeles

Sharon M. Hudson, PhD1, Karla D. Wagner, MA1, and Peter Kerndt, MD, MPH2. (1) Health Research Association, 3580 Wilshire Blvd., Suite 1660, Los Angeles, CA 90010, 213-736-6017,, (2) Los Angeles County Department of Health Services Sexually Transmitted Disease Program, 2615 S. Grand Ave., Rm. 500, Los Angeles, CA 90007

Objective: Identify factors influencing injection drug usersí (IDUís) exposure to and vaccination against hepatitis A virus (HAV) and hepatitis B virus (HBV), and settings where IDU access vaccination. Methods: Participants: 15-30 years old; reported injecting non-prescribed drugs at least once in past 6 months; recruited in Los Angeles for a multi-site behavioral intervention. Assessment included computer-administered questionnaire and blood draw. Samples tested for past infection by measuring total HBV core antibody and total hepatitis A antibody. Results: Of 285 individuals, 74% were male, 23% female and 3.2% transgender. Median age was 23 years. Over a third (37%) did not complete high school. Tests showed that 21% had been exposed to HBV and 23% to HAV. Chi-square tests for age and gender showed that 15-21 year-olds and transgender persons were significantly more likely to test HBV-positive (similar but NS results found for HAV). There was a non-significant trend for increasing exposure with higher education. More reported vaccination against HBV (47%) than HAV (31%). The most common reason for no prior vaccination was not knowing a vaccine existed. Community clinics and private physicians most commonly recommended and provided vaccine. Although 78% had been incarcerated, only 10% of these had been vaccinated there. Conclusions: Younger and transgender IDU are at high risk for HBV and HAV. There are multiple missed chances to inoculate them. Providing vaccine in correctional facilities is a key underused opportunity. A trend of increasing infection with schooling may support the CDC recommendation to provide school-age adolescents with HBV vaccine.

Learning Objectives:

Keywords: Drug Injectors, Hepatitis B

Presenting author's disclosure statement:
I do not have any significant financial interest/arrangement or affiliation with any organization/institution whose products or services are being discussed in this session.

Risk Behaviors and HIV, HBV, and HCV Injections Among Young Adult IDUs: CIDUS III/Drug Users Intervention Trial

The 131st Annual Meeting (November 15-19, 2003) of APHA