The 131st Annual Meeting (November 15-19, 2003) of APHA

Abstract #61089

Michiyo Hashimoto, PhD¹, Midori Nishiyama, MD, PhD¹, Masami Orui, MD, PhD², Takahiro Usami, PhD¹, and Kimihiro Nakae, PhD¹. (1) Department of Public Health Sciences, Dokkyo University School of Medicine, Mibu-machi, Shimotsuga-gun, Tochigi, 321-0293, Japan, +81-282-87-2133, michiyoh@dokkyomed.ac.jp, (2) Department of Health Care, Dokkyo University School of Medicine, Mibu-machi, Shimotsuga-gun, Tochigi, 321-0293, Japan

Increases in the number of Type 2 Diabetes (T2DM) patients in Japan have been reported, and this disease has become a major public health concern. By cross-sectional study, the prevalences of impaired fasting glucose (IFG), impared glucose tolerance (IGT), and T2DM were obtained by patients screened in 1992 (N=1,112) and 2000 (N=849) at a private hospital in suburban Tokyo. All subjects underwent a physical examination, blood pressure measurement, blood sampling, and oral glucose tolerance test (OGTT). For diagnoses of OGTT, the WHO criteria were used. A cohort study was also conducted with 210 subjects who had received a check-up in both 1992 and 2000 to investigate the risk factors of IFG and IGT. The prevalences were normal glucose tolerance (NGT) 76.4%, IFG 2.0%, IGT 15.3%, T2DM (previously and newly diagnosed) 6.3% in 1992, and 68.4%, 3.4%, 18.7%, 9.5% in 2000, respectively. A significantly lower prevalence of NGT and higher prevalences of IFG, IGT, and T2DM were observed in 2000 than in 1992. In the 8-year cohort study, 11.9% maintained IFG/IGT status while 12.8% progressed from NGT to IFG/IGT. NGT subjects who progressed to IFG/IGT showing significant increment in BMI, AST, ALT, GGT, and TG over 8 years compared to those of subjects who maintained NGT or IFG/IGT status, suggesting that obesity, liver dysfunction, and high TG are associated with development of IFG/IGT over an 8-year course.

Learning Objectives:

• Describe the prevalences of IFG, IGT, and Type 2 Diabetes in a suburban area of Tokyo.
• Identify risk factors of IFG and IGT 8 years prior to the diagnosis.
• Recognize the Japanese health care policy and characteristics of subjects who received a check-up.

Keywords: Diabetes, Health Assessment

Presenting author's disclosure statement:
I do not have any significant financial interest/arrangement or affiliation with any organization/institution whose products or services are being discussed in this session.