 | The 131st Annual Meeting (November 15-19, 2003) of APHA |
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| The 131st Annual Meeting (November 15-19, 2003) of APHA |
Danielle C. Ompad, PhD, Sandro Galea, MD, MPH, Yingfeng Wu, MA, Jennifer Ahern, MPH, and David Vlahov, PhD. Center for Urban Epidemiologic Studies, New York Academy of Medicine, 1216 Fifth Avenue, New York, NY 10029, 212-419-3589, dompad@nyam.org
Reports suggest a resurgence of PCP use in urban areas in the U.S. We assessed the role of period and birth cohort effects in age of first PCP use in NYC during the past forty years. We used data collected from two surveys of street-recruited drug users (DUs) [CIDUS II (Harlem site; n=208) and HOPE (n=689)] between 1997-2002. Among 897 DUs analyzed (male=70.4%, Hispanic=59.0%, black=28.9%, mean age=27.8), 44.1% reported ever using PCP. Use of other drugs including cocaine (OR=2.36, 95% CI=1.14-4.88), heroin (OR=1.61, 95% CI=1.04-2.50), crack (OR=1.82, 95% CI=1.23-2.69), and LSD (OR=5.63, 95% CI=4.04-7.86) was associated with PCP in a multivariable logistic model controlling for relevant covariates. In Kaplan-Meier (K-M) survival analyses, age at first PCP use was significantly older in the >=1990 period than in the <1990 period (p<0.0001) and in more remote birth year cohorts (e.g., 1961-65) compared to more recent birth year cohorts (e.g., 1981-85; p=0.0008). Period of first use (p<0.0001) and birth cohort (p=0.027-0.24) were predictors of age of first PCP use in separate multivariable proportional hazards models adjusting for covariates including age and use of other drugs. Period and birth cohort effects appear to be present in an analysis of the age of first PCP use during the past forty years. DUs born before 1970 started PCP at an older age than DUs born since 1970, and age of first PCP use has been older since 1990 than it was before 1990. Changes in concomitant drug use may explain some of these differences.
Learning Objectives:
Keywords: Drug Abuse, Epidemiology
Presenting author's disclosure statement:
I do not have any significant financial interest/arrangement or affiliation with any organization/institution whose products or services are being discussed in this session.