Julie C. McLaughlin, MS, MPH¹, Aruna V. Sarma, PhD², Rodney Dunn, MS¹, Kathleen A. Cooney, MD³, James E. Montie, MD⁴, John T. Wei, MD⁵, and David Schottenfeld, MD⁶. (1) Urology, University of Michigan, 1016 Women's Trailer, 1500 E. Medical Center Dr., Ann Arbor, MI 48109, 734-663-7428, juliecm@med.umich.edu, (2) Urology, Epidemiology, University of Michigan, 1016 Women's Trailer, 1500 E. Medical Center Dr., Ann Arbor, MI 48109, (3) Internal Medicine and Veterans Health Administration, University of Michigan, 7310 CCGC, Box 0946, 1500 E. Medical Center Drive, Ann Arbor, MI 48109, (4) Urology Surgery, University of Michigan, 2916 TC, 1500 E. Medical Center Dr., Ann Arbor, MI 48109, (5) Department of Surgery/Urology, The University of Michigan, 2916 Taubman Center, 1500 E. Medical Center Drive, Ann Arbor, MI 48109-0330, (6) Department of Epidemiology, School of Public Health, The University of Michigan, 109 S. Observatory, Ann Arbor, MI 48109-2029

Although coronary heart disease is the leading cause of death and morbidity in African-American adult men, relatively little is known about the predictors of heart disease in this population. The objective of the current study was to examine the associations between myocardial infarction (MI) and lifestyle risk factors in a community based-sample of 817 African-American men aged 40-79. We found the overall prevalence of MI increased with age, from 5.1 % among men aged 40-49 to 20.9 % among men aged 70-79. In multivariate logistic regression analyses adjusting for age, self-reported hypertension and diabetes, increasing physical activity was inversely associated with prevalence of MI. Men with moderate and high total energy expenditure had odds ratios of 0.49 (0.25, 0.96) and 0.29 (0.12, 0.68) for MI, respectively, as compared to men who were relatively inactive. Obese men had 2.20 (1.06, 4.55) fold the odds of a history of MI as compared to men who had a normal BMI, and current cigarette smokers had an OR of 2.73 (1.36, 5.49) for prevalence of MI. Our results suggest physical inactivity, obesity, and cigarette smoking are risk factors for MI in African-American men, and warrants further investigation of these relationships in future longitudinal studies.

Learning Objectives:

• At the conclusion of the session, the participant (learner) in this session will be able to describe risk factors for myocardial infarction in African-American men.

Presenting author's disclosure statement:
I do not have any significant financial interest/arrangement or affiliation with any organization/institution whose products or services are being discussed in this session.