Zahid Rathore, MPH1, Warren B. Sateren, MPH2, Philip O. Renzullo, PhD, MPH3, Mark J. Milazzo3, Darrell E. Singer, MD2, and Jose L. Sanchez, MD2. (1) Department of Epidemiology and Biostatistics, The George Washington University, School of Public Health & Health Services, 1901 Ingleside Terrace, NW, # 302, Washington, DC 20010, 202-986-4460, firstname.lastname@example.org, (2) Division of Retrovirology, WRAIR, U.S. Military HIV Research Program, 1 Taft Court, Suite 250, Rockville, MD 20850, (3) Henry M. Jackson Foundation, U.S. Military HIV Research Program, 1 Taft Court, Suite 250, Rockville, MD 20850
Background: The purpose of this project is to evaluate HIV-1 infection trends among active duty United States Army personnel, tested between 1985 and 2003. Long term follow-up of cohorts offers the opportunity to determine the rate and risk of new HIV-1 infections. Young men and women from every area of the United States are continuously joining the U.S. Army and are tested for HIV-1 on a periodic basis. This testing program provides unique insights into HIV-1 infection in a group of racially and ethnically diverse, sexually active men and women from every area in the United States.
Methods: The U.S. Army routinely tests personnel for HIV-1 which allows for the characterization of demographic risk factors for infection (incidence rate calculations and unadjusted and adjusted relative risk [RR] estimates with 95% CIís). Rates are calculated by age group, race/ethnicity, gender, marital status, length of service, education level, rank, and military job occupation. Geographic distribution will be analyzed by county of residence.
Results: Incidence declined between 1985 and 2003 from 0.46 cases / 1,000 person-years [py] to 0.07 cases / 1,000 py. After adjusting for all variables, males (RR = 3.18), blacks (RR = 4.63), personnel between 25 and 29 years old (RR = 1.58) and non-married personnel (RR = 1.82) were at greatest risk for HIV-1 infection.
Conclusion: U.S. Army personnel provide a unique cohort for characterizing long-term trends in HIV-1 incidence. Application of the results will assist in identifying and targeting high-risk populations in prevention efforts.
Presenting author's disclosure statement:
I do not have any significant financial interest/arrangement or affiliation with any organization/institution whose products or services are being discussed in this session.
Handout (.pdf format, 987.6 kb)
The 132nd Annual Meeting (November 6-10, 2004) of APHA