Recorded presentation

Devon Payne-Sturges, DrPH, Office of Policy, Economics and Innovation, U.S. EPA, Ariel Rios Bldg. MC1809T, 1200 Pennsylvania Ave., NW, Washington, DC 20460, 202 566-2316, payne-sturges.devon@epa.gov, Daniel A. Axelrad, Office of Policy, Economics and Innovation, US Environmental Protection Agency, 1200 Pennsylvania Ave NW, Mail Code 1809, Washington, DC 20460, Rosemary Castorina, PhD, MPH, Center for Children's Environmental Health Research, UC Berkeley School of Public Health, 2150 Shattuck Ave., Suite 600 MC 7380, Berkeley, CA 94720-7380, and Tracey J. Woodruff, PhD, MPH, Office of Policy, Economics and Innovation, United States Environmental Protection Agency, 75 Hawthorne Street (SPE-1), San Francisco, CA 94105.

The purpose of Environmental Public Health Tracking (EPHT) is to implement a national tracking system to monitor data about environmental hazards and exposures and data about diseases that are possibly linked to the environment. This will provide information to federal, state, and local agencies, and communities that can be used to plan, apply, and evaluate actions to prevent and control environmentally related diseases. Biomonitoring of exposure to environmental contaminants in humans is an important part of tracking. However, relatively little information is available to assess the health context of measured concentrations of environmental contaminants in humans. Organophosphate (OP) pesticide exposures estimated from biomonitoring data are strong candidates for inclusion in EPHT for several reasons: 1) wide use of OP pesticides in both agricultural and residential settings; 2) available methods for measuring body burdens; and 3) availability of toxicity information to assist in a health based interpretation of OP biomonitoriong data. The objectives of our study are to develop a methodology for a health risk interpretation of biomonitoring data, and apply it using NHANES 1999 body burden data for OP pesticides as a case study. We back calculated OP pesticide exposures from urinary metabolite data and compared with available toxicity information using data from U.S. EPA Office of Pesticide Programs. This is one method for assessing the health context of OP pesticide exposures and can be used as an example of how to put biomonitoring data in context for EHPT.

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