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American Public Health Association
133rd Annual Meeting & Exposition
December 10-14, 2005
Philadelphia, PA
APHA 2005
 
3236.0: Monday, December 12, 2005 - Board 1

Abstract #110770

Exercise and bone mineral density at the femoral neck in postmenopausal women: A meta-analysis of controlled clinical trials using individual patient data

George A. Kelley, DA and Kristi S. Kelley, MEd. School of Medicine, Department of Community Medicine, West Virginia University, Robert C. Byrd Health Sciences Center, PO Box 9190, Morgantown, WV 26506-9190, 304-293-6279, gkelley@hsc.wvu.edu

The purpose of this study was to conduct a meta-analysis using individual patient data (IPD) in order to examine the efficacy of exercise for improving bone mineral density (BMD) at the femoral neck in postmenopausal women. Ten controlled clinical trials that included 595 subjects ages 42 to 92 years met our criteria for inclusion. Across all designs and categories, there was an increase in BMD of 0.73 +/- 5.52% and 0.45 +/- 6.78% respectively, in the exercise and control subjects. However, comparison of initial and final BMD values between exercise and control subjects revealed no statistically significant effect of exercise on femoral neck BMD. In addition, random-effects analyses revealed no statistically significant within or between-group differences for studies in which IPD were available versus those that were not. In conclusion, the results of this study suggest that exercise is not efficacious for improving and/or maintaining femoral neck BMD in postmenopausal women. However, a need exists for additional research in this area before clinical recommendations can be made regarding the effectiveness of exercise for improving and/or maintaining femoral neck BMD in postmenopausal women.

Learning Objectives: At the end of this session, the participant will be able to

Keywords: Exercise, Aging

Presenting author's disclosure statement:

I wish to disclose that I have NO financial interests or other relationship with the manufactures of commercial products, suppliers of commercial services or commercial supporters.

Research Issues among Older Adults

The 133rd Annual Meeting & Exposition (December 10-14, 2005) of APHA