Back to Annual Meeting Page		American Public Health Association 133rd Annual Meeting & Exposition December 10-14, 2005 Philadelphia, PA

Abstract #113698

Yunyin W. Hu, MPH¹, Amy R. Wohl, MPH, PhD¹, and Dennis Deapen, Dr PH². (1) HIV Epidemiology Program, Los Angeles County Department of Health Services, 600 S. Commonwealth Ave., Suite 1260, Los Angeles, CA 90005, 213-351-8142, vhu@ladhs.org, (2) Cancer Surveillance Program, Keck School of Medicine of USC, 1540 Alcazar Street, Suite 204, Los Angeles, CA 90033

Background: Few data exist on patterns of AIDS-related malignancies among US-born Latinos compared to foreign-born Latinos. Methods: Data were examined for 10,603 Latino persons diagnosed with AIDS in Los Angeles County between1990 and 2002. Data on AIDS-defining malignancies was obtained from AIDS and cancer surveillance registries as part of the National AIDS/Cancer Registry Match project. Multivariate modeling was used to examine the association between country of origin and total and individual AIDS-related malignancies, controlling for age, gender, mode of HIV transmission, and facility type. Results: Among the Latinos born outside of the US, 67% were born in Mexico and 24% were born in Central America. US-born Latinos with AIDS were more likely to have any AIDS-related malignancy when compared to foreign-born Latinos with AIDS (18% vs. 14%; P<0.0001). Diagnoses of Kaposi's Sarcoma (KS) and lymphoma were higher among US-born Latinos with AIDS compared to foreign-born Latinos with AIDS (14% vs. 11%; p< 0.0001 and 4% vs. 3%; p=0.034, respectively). Elevated adjusted odds ratios(OR) were found for Kaposi's sarcoma (OR=1.3, 95% CI: 1.1-1.4), and lymphoma (OR=1.3 95% CI: 1.0-1.6) among US-born Latinos. Other independent risk factors for any AIDS-defining malignancy included male gender (OR=2.0, 95% CI: 1.5-2.7) and a history of male-to-male sex (OR=2.5, 95% CI: 2.2-3.0). Conclusion: These data show increases in AIDS-related malignancies among US born Latinos when compared to foreign-born Latinos with particular increases in KS and lymphoma. Further studies are needed to investigate possible factors that may explain these differences.

Learning Objectives:

• Identify the differences in AIDS-related malignancies between US-born Latinos and foreign-born Latinos with AIDS.
• Analyze surveillance data using multivariable logistic regression models.
• List two or three factors associated with higher occurrence of AIDS-related malignancies.
• Develop other co-morbidity projects through record linkage between surveillance data and other public health data.

Keywords: HIV/AIDS, Cancer

Presenting author's disclosure statement:

I wish to disclose that I have NO financial interests or other relationship with the manufactures of commercial products, suppliers of commercial services or commercial supporters.