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133rd Annual Meeting & Exposition December 10-14, 2005 Philadelphia, PA |
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Lawrence H. Moulton, Department of International Health, The Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe St., Baltimore, MD 21205, 410-955-6370, lmoulton@jhsph.edu
Cluster-randomized studies with relatively small numbers of clusters can be unbalanced on important covariates across treatment arms if randomization is not constrained sufficiently. I focus on a particular type of study, a "stepped-wedge" design in which clinics are randomized to an entry sequence. An example of a tuberculosis intervention study in Brazil will be elaborated. Relevant analysis considerations will also be mentioned.
Learning Objectives:
Keywords: Biostatistics, Tuberculosis
Related Web page: www.tbhiv-create.org/
Presenting author's disclosure statement:
I wish to disclose that I have NO financial interests or other relationship with the manufactures of commercial products, suppliers of commercial services or commercial supporters.
The 133rd Annual Meeting & Exposition (December 10-14, 2005) of APHA