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133rd Annual Meeting & Exposition
December 10-14, 2005
Janet T. Eyster, PhD, Claudia Holzman, DVM, MPH, PhD, and Veronika Skorokhod, MS. Department of Epidemiology, Michigan State University, College of Human Medicine, B601 West Fee Hall, E. Lansing, MI 48824, (517) 353-8623, firstname.lastname@example.org
Previous studies with adult women suggest that preterm delivery (PTD) rates are lowest for women in their 20's and increase with advancing age, the increase occurring at an earlier age in Blacks than in Whites. To examine age-related patterns of PTD, the multi-site MODE project linked birth certificate and census data and created a measure of neighborhood deprivation. Women who delivered a singleton live infant were divided into four strata based on ethnicity (White non-Hispanic [WNH] and Black non-Hispanic [BNH]) and smoking status. Multi-level models were used to assess associations between maternal age, neighborhood deprivation score, age-deprivation interactions and risk of PTD in each stratum. In WNH non-smokers, PTD rates were significantly increased in higher deprivation neighborhoods at all ages. Elevated PTD risk with advancing maternal age was noted only in women age 35-39 living in high deprivation neighborhoods. In WNH smokers, deprivation scores had less influence on PTD rates. The effect of increased PTD risk with advancing maternal age was evident at age 30-34 in high deprivation neighborhoods only, and at age 35-39 for all WNH smokers. In BNH non-smokers PTD rates increased for all women age 30 and over, with the advanced maternal age effect being significantly stronger in high deprivation neighborhoods. In BNH smokers, there was no significant effect of neighborhood deprivation, but PTD rates were significantly higher with maternal age > 25. These analyses suggest that modeling high-risk behaviors such as individual-level smoking and neighborhood deprivation may help to elucidate relationships between maternal age and PTD.
Keywords: , Pregnancy Outcomes
Presenting author's disclosure statement:
I wish to disclose that I have NO financial interests or other relationship with the manufactures of commercial products, suppliers of commercial services or commercial supporters.
The 133rd Annual Meeting & Exposition (December 10-14, 2005) of APHA