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133rd Annual Meeting & Exposition
December 10-14, 2005
Marian Pavuk, MD, PhD, SpecPro, Inc., 12500 San Pedro Ave., Suite 670, San Antonio, TX 78216, Joel Michalek, Air Force Research Laboratory, US Air Force, 2655 Flight Nurse, Building 807, Brooks City-Base, TX 78235, Arnold Schecter, MD, MPH, University of Texas, School of Public Health, 5323 Harry Hines Blvd., Room V8, 112E, Dallas, TX 75390-9128, 214-648-1096, firstname.lastname@example.org, Norma S. Ketchum, MS, Air Force Research Laboratory, 2655 Flight Nurse, Brooks City-Base, TX 78235, Fatema Z. Akhtar, MS, The Start Center, 3939 Medical, Suite100, San Antonio, TX 78249, and Karen A. Fox, MD, School of Aerospace Medicine, US Air Force, 2601 Louis Bauer Drive, Brooks City-Base, TX 78235.
Abstract Objective: To examine cancer incidence in 1,482 Air Force veterans who served in Southeast Asia (SEA) and were not occupationally exposed to herbicides.
Methods: Cancer incidence between 1982 and 2003 was determined by record review and Cox proportional hazards models were used to estimate risk ratios across serum TCDD and years served in SEA categories.
Results: All sites cancer risk increased with TCDD (RR=1.6, 95% CI 1.2-2.2). The risk of prostate cancer increased with years of SEA service but not with TCDD. TCDD and years of SEA service interacted with all sites cancer; the risk was greatest in those with the highest TCDD levels and the longest time served in SEA.
Conclusions: These results suggest non-occupational exposures to TCDD or other factors while in SEA may contribute to cancer risk in these veterans.
Presenting author's disclosure statement:
I wish to disclose that I have NO financial interests or other relationship with the manufactures of commercial products, suppliers of commercial services or commercial supporters.
The 133rd Annual Meeting & Exposition (December 10-14, 2005) of APHA