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Improving colorectal cancer (CRC) survival in Asians: Are there disparities in early detection?

Michelle Agustin Aranda, MPH1, Evan Sekeris, PhD1, Marcia L. McGory, MD1, David S. Zingmond, MD, PhD1, Roshan Bastani, PhD2, and Clifford Y. Ko, MD, MSHS, FACS1. (1) Center for Surgical Outcomes and Quality, University of California, Los Angeles, 10833 Le Conte Avenue, CHS 72-215, Los Angeles, CA 90095, 310-478-3711 x 41243, magustin@mednet.ucla.edu, (2) Department of Health Services, University of California, Los Angeles, School of Public Health, Box 951722, Los Angeles, CA 90095

Background: CRC screening/early detection are closely linked to improved survival rates. Asians tend to have lower screening rates compared to Whites, but little is known about CRC screening amongst Asian races. Our objective is to compare the rates of early detection for several Asian races.

Methods: All CRC patient data from the California Cancer Registry from 1991-2000 were linked to the California Inpatient File and the 2000 Census. Ordered logit regression was performed to identify predictors of early detection (i.e. Stage 0, I, II) using variables including age, gender, comorbidities, social economic status, insurance, tumor location (distal/proximal), and race. Asian cohorts were categorized as: Chinese, Eastern (Japanese/Koreans), Southern (e.g. Indian), and Asian Pacific Islander (API).

Results: 65,520 CRC patients were identified; 8% were Asians. For Asians, 32% were Chinese, 29% Eastern, 38% Southern, and 1% API. Mean age was 70 years (Asians: 66 years). Asians were less likely than Whites to be diagnosed with early stage CRC (OR 0.90, p < 0.05). Amongst Asians, there were no significant differences for Chinese and API, however, Southern Asians were the least likely have early stage CRC (OR 0.86, p<0.05), followed by Eastern Asians (OR 0.90, p< 0.05).

Conclusions: There are significant disparities in the early detection of CRC for Asians compared to Whites. Amongst Asians, Southern and Eastern Asians have significantly lower rates. Since effective screening is essential in the detection of early stage disease (and for improving survival rates), further work needs to improve screening rates specific to these groups.

Learning Objectives:

Presenting author's disclosure statement:

Not Answered

Cancer Risk Factors, Prevention, and Treatment in AAPI Communities

The 134th Annual Meeting & Exposition (November 4-8, 2006) of APHA