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APHA Scientific Session and Event Listing

Shin Yi Jang¹, Shin Yi Jang², Eun-Young Ju¹, Sung-Il Cho¹, Duk-Kyung Kim², and Seung Wook Lee¹. (1) Graduate School of Public Health, Seoul National University, 28 Yeongeon-Dong, Jongno-Gu, Seoul, 110-460, South Korea, 82-2-3410-2754, bautai01@hotmail.com, (2) Samsung Medical Center & Cardiac and Vascular Center, Sungkyunkwan University School of Medicine, 50 Ilwon-Dong Kangnam-Gu, Seoul, 135-710, South Korea

The aim of this study was to show the association between risk factors of coronary artery disease and H. pylori infection confirmed by gastroscopic biopsy.

The study conducted on 211 men and 65 women aged 20 years and older. Patients had the result of gastroscopic biopsy. They had been examined from July 1995 to July 2002 at the Center of Health Promotion and Sports Medicine in Samsung Medical Center, Seoul, Korea. Informations were taken after reviewing medical chart.

The mean age was 52.4(±9.42). The positive rate of H. pylori infection in this study was 88%. There was significant positive association between H. pylori colonization and age(p=0.023). SBP, DBP, BMI, DM, WBC, Fibrinogen, TC, TG, LDL, HDL and the ratio of LDL to HDL levels were correlated with risk factors of atherosclerosis(p<0.05), but H. pylori colonization was not associated with them in a multiple logistic regression analysis.

The status of H. Pylori infection in now may not be independent risk factor of coronary artery disease, and could not observe to association with hypertension, diabetes, obesity, coagulation factor, inflammatory marker and lipid profiles.

Key words : Helicobacter pylori infection, coronary artery disease risk factors, atherosclerosis

Learning Objectives:

• Atherosclerosis is the leading cause of coronary artery disease.
• Recent studies have demonstrated a relationship between risk factors of coronary artery disease and H. pylori infection. The aim of this study was to show the association between risk factors of coronary artery disease and H. pylori infection confirmed by gastroscopic biopsy.

Keywords: Helicobactor pylori, Chronic (CVD)

Presenting author's disclosure statement:

Not Answered