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APHA Scientific Session and Event Listing

Ximena Urrutia-Rojas, DrPH, RN¹, Sejong Bae, PhD², Walter McConathy, PhD³, John Menchaca, MD⁴, Maria Jimenez, MD, MPH¹, Mary Luna-Hollen, PhD, RD¹, Andras Lacko, PhD⁵, Khiya Marshall, MPH⁶, Rosie Rojas¹, Lada Alexeenko, MD, MPH¹, and Craig Spellman, PhD, DO³. (1) Dept of Social & Behavioral Sciences, UNT Health Science Center School of Public Health, 3500 Camp Bowie Blvd. EAD1-711A, Fort Worth, TX 76107, 817-735-0325, xurrutia@hsc.unt.edu, (2) Epidemiology, UNT Health Science Center School of Public Health, 3500 Camp Bowie Blvd - CBH 338, Forth Worth, TX 76107, (3) Internal Medicine, UNT Health Science Center School of Medicne, 3500 Camp Bowie Blvd - PCC 313, Fort Worth, TX 76107, (4) Pediatrics, Cook’s Children’s Physician Network, Fort Worth, TX, 800 8th Ave. #124., Fort Worth Texas, TX 76104, (5) Molecular Biology & Immunology, UNT Health Science Center, 3500 Camp Bowie Blvd, Fort Worth, TX 76107, (6) Social and Behavioral Sciences, UNTHSC School of Public Health, 3500 Camp Bowie Blvd., Fort Worth, TX 76107

Overweight and diabetes and CVD family history in children indicate increased risk for these diseases at an earlier age. Overweight Hispanic children with family history of diabetes (250) and their siblings (213), ages 7 to 17 years old, were examined for T2DM and CVD risk factors based on physical examination, family history, and laboratory studies. One half (53%) were female. Mean age was 11.1 and 11.4 years for females and males respectively. Three fourths (76.8%) were overweight/obese (BMI>85th%). One third of girls (31.6%) and 13.3% of boys exceeded the waist circumference values of 88cm. and 100cm. identified as the cutoff points for increased risk of obesity related comorbidities in adults. Although not in the hypertensive range, over one third had elevated systolic BP. Fasting glucose was elevated (>100mg/dl) in 6.8%, and 25.1% had elevated insulin levels (°Ý15uU/mL). Close to 1/3 had elevated triglycerides (>150); 47.7% had total cholesterol>160 with 9.9% at>199. LDL-Cholesterol>90 and >129 was found in 48.7% and 6.6% respectively. Over two thirds (68.1%) had HDL-Cholesterol<50 and 5.1%< 32. With one exception (girls were more likely to have elevated insulin levels), no significant differences were found between boys and girls. These findings indicate that overweight and family history of diabetes can be markers of an increase in the severity of risk for T2DM and CVD in Hispanic children. The short and long term public health implications of these findings should guide the primary prevention of overweight and genetic related chronic diseases as early as possible in vulnerable groups.

Learning Objectives: At the end of presentation the participants will

• Discuss overweight and family history of diabetes as risk factors for type 2 diabetes and cardiovascular disease in children.
• Recognize elevated values of anthropometric and blood parameters related to risk for type 2 diabetes and cardiovascular disease in children.
• Recognize the need for primary prevention of overweight and genetic related chronic diseases as early as possible in vulnerable groups.

Presenting author's disclosure statement:

Not Answered