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APHA Scientific Session and Event Listing

Recorded presentation

Peter A. Leone, MD, School of Medicine- Division of Infectious Diseases, The University of North Carolina at Chapel HIll, 130 Mason Farm Road, CB 7030, Chapel Hill, NC 27514, 919-843-0724, pal007@med.unc.edu

The interactions between HIV infection and herpes simplex virus type 2 (HSV-2) infection are complex and important from both public health and clinical management perspectives. Genital herpes significantly increases the risk of HIV infection in people who are exposed to HIV. Equally as important, co-infection with HSV-2 and HIV complicates the clinical course of HIV infection and management, may increase the rate of HIV disease progression, and increases the amount and frequency of HIV mucosal shedding during clinical or subclinical HSV reactivation. Although a high proportion of HIV infected people are co-infected with HSV-2 (between 60%-80%, which is at least twice the US rate in those not HIV-infected), many people with HSV-2 infection do not know they are infected. The availability of type specific tests allows diagnosis of HSV infection in people who do not have clinical symptoms and is an important management tool to allow full consideration of options for optimal therapy of both the HIV and HSV-2 infections.

Learning Objectives:

• See session abstract

Presenting author's disclosure statement:

Any relevant financial relationships? No

Recorded presentation