149625 Vitamin D Deficiency Epidemic: Consequences for Health

Monday, November 5, 2007: 8:30 AM

Michael F. Holick, PhD, MD , Dept of Medicine/Endocrinology, Nutrition and Diabetes, Boston University School of Medicine, Boston, MA
Vitamin D deficiency is often equated with rickets. Since rickets is no longer seen by physicians, it is assumed that vitamin D deficiency was conquered with the fortification of milk with vitamin D. However, it has been reported that more than 50% of adults of over the age of 65, 42% of African American women aged 15-49, 52% of adolescent Hispanic and black children, and 48% of preadolescent white girls were vitamin D deficient. Pregnant women receiving a prenatal vitamin were also not only at high risk, but so were their infants. Seventy-six percent of mothers and 81% of infants at the time of birth were vitamin D deficient.

Not only does vitamin D deficiency prevent maximum bone growth and deposition of bone mineral in children, it will precipitate and exacerbate osteoporosis later in life and causes the painful bone disease osteomalacia. Vitamin D deficiency has been linked to increased risk of serious chronic diseases including type I diabetes, multiple sclerosis, rheumatoid arthritis, Crohn's disease, cardiovascular disease as well as many deadly cancers including the prostate, pancreas, colon, and esophagus.

Children and adults require 1,000 IU of vitamin D3/d if they are not exposed to sunlight. Diet cannot provide this amount, and, thus, sensible sun exposure and/or supplements are needed.

Measurement of 25-hydroxyvitamin D is the only way to determine a person's vitamin D status. All health care professionals should be alert to this epidemic and institute treatment and preventative measures.

Learning Objectives:
At the conclusion of the session, the participants will be able to: 1. Discuss vitamin D deficiency in pregnant women, neonates, children, young, middle aged and older adults. 2. Provide health care professionals with knowledge about how to determine a person’s vitamin D status. 3. Provide prevention and treatment strategies for vitamin D deficiency -- including diet and sunlight. 4. Describe new insights about the importance of the biologic function of vitamin D not only for bone health, but also for prevention of autoimmune diseases, deadly cancers, heart disease and infectious diseases.

Keywords: Child Health, Vitamins

Presenting author's disclosure statement:

Any relevant financial relationships? No
Any institutionally-contracted trials related to this submission?

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.