172902 Examining the role of Stress events and Depressive Symptoms on Birth Outcomes in a Sample of Chilean Low-Income Pregnant females

Monday, October 27, 2008: 2:40 PM

Miguel Cordero , Research and Studies Department, Ministry of Health of Chile, Santiago, Chile
Paula B. Repetto, PhD , Psychology, Universidad Catolica de Chile, Santiago, Chile
M. Leonor Bustamante , Program of Human Genetics, Faculty of Medicine, University of Chile, Santiago, Chile
Eliana Guic, PhD , Department of Psychology, P. Universidad Catolica de Chile, Santiago, Chile
Luis Medina, MD , Department of Obstetrics and Gynecology, Catholic University of Chile, Center for Perinatal Diagnosis and Research, Dr. Sótero del Río Medical Center Hospital, Santiago, Chile
Ricardo Gomez, MD , Department of Obstetrics and Gynecology, Catholic University of Chile, Center for Perinatal Diagnosis and Research, Dr. Sótero del Río Medical Center Hospital, Santiago, Chile
Preterm delivery is considered to be the leading cause of perinatal morbidity and mortality worldwide. The determinants of this condition are several, however, researchers have discussed the role that psychosocial factors may have. Among these, , maternal tress and depression have been described as factors that influence birth outcomes, in particular premature birth, among females (e.g. Ritter et al., 2000; Rich-Edwards & Grizzard, 2005).

We conducted a prospective study with a sample of 734 Chilean non-smokers females participated. We examined if numbers of stressors (PRAMS) to which these females were exposed and levels of depressive symptomatology (CES-D) measured during the first visit (week 12th) predicted premature birth (births before 35 weeks), controlling for other predictors of premature birth. Of the 734 females who participated, only 34 gave birth before 37 weeks.

Our findings suggest that stress events but not depressive symptoms predicts premature birth , even when we control for education, income, social support and antecedents of premature birth. Interestingly, we found that stress had an effect only after certain number of events these women face. Using a threshold of 4, as has been described previously in the literature, we found that stress events started to have an effect on pregnancy outcomes.

Economic difficulties, problemas with their partners and domestic violence were the stressors that these females most commonly faced. These findins are consistent with waht other researchers have described regarding the role of life events on preterm brith (Dole et al., 2003). We present other findings, and discuss explanations and potential implications of these results for public health policies.

Learning Objectives:
- Recognize the role of stressors that low income females face and their impact on pregnancy outcomes. - Describe types of stressors that low income pregnant females most commonly face. - Discuss the role of stress and depressive symptoms that may have on premature birth.

Keywords: Pregnancy Outcomes, Stress

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: Have participated in the design of the study, data collection, analyses and discussion of results.
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.