183872 T. vaginalis and C. trachomatis: Whom should we screen?

Monday, October 27, 2008: 10:35 AM

Sylvia Tan, MS , Research Triangle Institute, Washington, DC
Susan M. Rogers, PHD , Statistics and Epidemiology, Research Triangle Institute, Washington, DC
Elizabeth Eggleston, DrPH , Health and Behavior Measurement Program, Research Triangle Institute, Washington, DC
Anthony Roman, MA , Center for Survey Research, University of Massachusetts-Boston, Boston, MA
Charles F. Turner, PhD , Health and Behavior Measurement Program, Research Triangle Institute, Washington, DC
Infections with T. vaginalis (Tv) and C. trachomatis (Ct) are common among young adults. Since the majority of infections are asymptomatic, screening is an effective strategy for prevention of long-term health effects. However, current guidelines recommend Ct screening only for women <25 years and there is no active surveillance of Tv in the U.S.

The Monitoring STIs study tracks the prevalence, over a 3-year period, of these sexually transmitted infections among a probability sample of young adults aged 15-35 years in Baltimore, Maryland an urban area with historically high rates of STIs. The study combines telephone surveys with STI testing of mail-in urine specimens. Data collection for the first year of the project was completed September 2007.

Preliminary findings from nearly 750 adults in year one suggest that Tv infections are common (6.3% overall), particularly among women (10.2%; OR=5.6, 95%CI 2.0, 15.3), and among those reporting a previous Tv diagnosis (OR=5.3, 95%CI 2.4, 11.6). Conversely, we detected more Ct infections among men (6.2%) than women (3.5%; OR=1.8, 95%CI 0.7, 4.3); however rates were significantly higher among those with previous Ct (OR=3.9, 95%CI 1.4, 9.9) and respondents aged 20 years or younger (OR=3, 95%CI 1.2, 7.6). Rates of both infections were higher among Blacks than other racial/ethnic groups.

These results suggest that within high-risk populations, public health interventions aimed at reducing STIs should consider Tv screening and expansion of Ct screening for men and persons with a history of previous infection.

Learning Objectives:
1.) Describe current guidelines for STI screening in the U.S. 2.) Assess preliminary findings from a population-based survey on STIs in Baltimore, Maryland. 3.) Recognize why preliminary results may suggest expanded STI screening within high-risk populations.

Keywords: STD Prevention, Screening

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I am a statistician for the Data Coordinating Center of the STIs Monitoring Study.
Any relevant financial relationships? Yes

Name of Organization Clinical/Research Area Type of relationship
RTI Statistics and Epidemiology Employment (includes retainer)

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.