186613 Helicobacter pylori, Protozoa, Helminths and Household Hygiene in a Binational Sample of a US-Mexico Border Population

Tuesday, October 28, 2008: 1:20 PM

Victor Cardenas, MD, MPH, PhD , El Paso Regional Campus, University of Texas School of Public Health, El Paso, TX
Kristina D. Mena, PhD , Division of Environmental Health, El Paso Campus, UT HSC at Houston School of Public Health, El Paso, VA
Melchor Ortiz, PhD , El Paso, Regional Campus, UT Health Science Center-School of Public Health, EL Paso, TX
SriTulasi Karri, PhD , Internal Medicine, Texas Tech University Health Science Center School of Medicine, Lubbock, TX
Easwaram Variyam, MD , Internal Medicine, Texas Tech University Health Science Center School of Medicine, Lubbock, TX, Andorra
Casey Barton Behravesh, DVM, DrPH, DACVP , Enteric Diseases Epidemiology Branch, Centers for Disease Control and Prevention, Atlanta, GA
JohnR Bristol, PhD , Department of Biological Sciences, University of Texas at El Paso, El Paso, TX
Lillian F. Mayberry, PhD , Department of Biological Sciences, University of Texas at El Paso, El Paso, TX
Ynes R. Ortega, PhD , Center for Food Safety, University of Georgia, Griffin, GA
Yoshihiro Fukuda, MD PhD , Clinical Nutrition and Health Science, Hyogo College of Medicine, Hyogo, Japan
Armando Campos, MD MSc , Medical Research HGZ 6, Mexican Institute ofocial Security, Ciudad Juarez, Mexico
David Y. Graham, MD , Internal Medicine -GI Research, Baylor College of Medicine /DeBakey VAMC, Houston, TX
In 2005, we investigated a random sample of households in El Paso, Texas and Ciudad Juarez, Chihuahua, Mexico to determine t prevalence of Helicobacter pylori, Cryptosporidium spp., Cyclospora spp., Giardia spp and Taenia spp using immunoassays. In addition, helminth eggs were quantified using a standard flotation technique. The prevalence of these agents was investigated in relation to selected characteristics and total and fecal coliform counts from environmental samples of kitchen surfaces, water, and hands of caregivers. The overall prevalence for this border region of H. pylori, Cryptosporidium spp., Giardia spp., Cyclospora spp., E. histolytica, E. dispar, and Taenia spp. infection were 38.2%,1.4%, 2.9%, 0%, 0%,1.2%, and 3.0% , respectively. One person had both A. lumbricoides and N. americanus. There was no evidence of microbiologic contamination of drinking water. Coliforms were found at low frequencies on hands of caregivers and the kitchen surfaces. Dish cloths/sponges, countertops and cutting boards were the most common contaminated sites. Not always washing hands after using the toilet had a 30% increase in the prevalence of H. pylori infection (prevalence ratio= 1.3; 95% CI=1.01.8). No associations were found with other pathogens, but given their low prevalence, the study had limited statistical power to detect them. Furthermore, no associations were found by microbiologic contamination for any pathogen. In multivariate analysis, age, education, crowding, not always washing hands, and place of birth were associated with prevalence of H. pylori. No association was found with living in Juarez vs. El Paso.

Learning Objectives:
Participants will learn about methods used to conduct population-based research on the US-Mexico border Participants will also learn estimates of the prevalence of H. pylori and other gastro-intestinal pathogens including protozoa and helminths Participants will learn too about factors related to H. pylori infection on both sides of the border, extending previous research done in this population. Keywords: Helicobacter pylori, parasitic infections, Health Surveys, US-Mexico Border

Keywords: Infectious Diseases, Helicobactor pylori

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: As biostatistician of the team, I participated in the planning, conduct and analysis of this study
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.