193585 Retention in the NIDA Clinical Trials Network Women and Trauma Study: Implications for post-trial implementation

Tuesday, November 10, 2009

Rogério M. Pinto, PhD , School of Social Work, Columbia University, New York, NY
Aimee Campbell, PhD , School of Social Work, Columbia University, New York, NY
Denise Hien, PhD , CUNY Department of Pyschology; Columbia University College of Physicians and Surgeons, City University of New York at CCNY; Columbia University, New York, NY
Gary Yu, MPH , Mailman School of Public Health, Columbia University, New York, NY
Prakash Gorroochurn, PhD , Mailman School of Public Health, Columbia University, New York, NY
Minority women's participation in substance use treatment clinical trials and community programs is low. Research is needed to suggest how tested treatments can be transported to minority communities. This study aims to identify factors that influence adherence and completion in the Women and Trauma Study, while identifying implications for implementation.

Methods:

Log-linear model used eleven predictors to determine contribution of organizational and demographic variables toward adherence (Zero-12 sessions). Logistic regression used same variables to model likelihood of completion (≥ 6 sessions).

Results:

353 women from seven organizations. 46% Caucasian; 34% African American; 7% Latinas; 14% multiracial. Mean number of sessions attended 6.8 (SD = 3.94); 199 (57%) completed treatment. Women in organizations E (AOR = 1.79; CI = 1.48, 2.16) and F (AOR = 1.41; CI = 1.17, 1.71) had better adherence rates. Those in E (AOR = 0.28; CI = 0.09, 0.89) lower completion rates. Latinas (AOR = 1.26; CI = 1.03, 1.52) and women reporting more education (AOR = 1.02; CI = 1.00, 1.04) had better adherence. Services prior to treatment (AOR = 1.06; CI = 1.02, 1.11) and length of treatment (AOR = 1.05; CI = 1.04, 1.06) predicted higher rates of adherence. Services received (AOR = 0.79; CI = 0.62, 1.00) and length of treatment (AOR = 0.82; CI = 0.76, 0.88) predicted completion.

Implications:

To retain women with trauma and substance use in trials and treatments, emphasis on modifiable organizational variables is crucial, as these are the most significant predictors of adherence and completion.

Learning Objectives:
1. Identify factors that influence adherence and completion in the NIDA Women and Trauma Study. 2. Evaluate implications of the implementation process as it relates to the NIDA Women and Trauma Study. 3. Discuss how modifiable organizational variables are a key component in the retention of minority women in substance use treatment clinical trials.

Keywords: Minority Health, Substance Abuse Treatment

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: (2006-present) Assistant Professor. Columbia University School of Social Work, New York, NY. (2003-2006) Postdoctoral Fellow. Columbia University College of Surgeons and Physicians. (2003-2005) Adjunct Professor. Graduate School of Social Services, Fordham University, New York, NY. (Fall 2002) Adjunct Professor. School of Social Work, Columbia University, New York, NY. Principal investigator on a Funded by the NIMH, the goal of this study is to identify factors that influence research collaboration and to test a model of collaboration among service providers. Principal Investigator on a study promoting community collaboration in scientific research. The study's goal is to define specific mechanisms involved in the development of community partnerships for research. It is a Research Fellowship awarded by the Columbia University Diversity Program. Principal Investigator of a pilot study examining a community-focused model of disease prevention in Brazil. The pilot study examines community-focused health service delivered by social work paraprofessionals in Brazil. Funded by the International Association of Schools of Social Work. Author or coauthor of 36 publications and book chapters primarily relating to social welfare and HIV-related research. Numerous national and international presentations. Numerous awards and citations for contribution to the profession of social work.
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.

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