197479 A Cross-sectional Study of Kidney function and Cardiovascular risk in Korean

Sunday, November 8, 2009

Shin Yi Jang , Graduate School of Public Health, Seoul National University, Seoul, South Korea
Shin Yi Jang , Samsung Medical Center, Cardiovascular Imaging Center, Seoul, South Korea
Eun Young Ju , Graduate School of Public Health, Seoul National University, Seoul, South Korea
Jin-Oh Choi , Department of internal medicine, Cardiovascular Imaging Center, Samsung Medical Center, Seoul, South Korea
Sang-Chol Lee , Department of internal medicine, Cardiovascular Imaging Center, Samsung Medical Center, Seoul, South Korea
Seung Woo Park , Department of internal medicine, Cardiovascular Imaging Center, Samsung Medical Center, Seoul, South Korea
Duk-Kyung Kim , Samsung Medical Center & Cardiac and Vascular Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
Seung Wook Lee , Department of Public Health, Graduate School of Public Health, Seoul National University, Seoul, South Korea
Background: The aim of this study is to estimate the cardiovascular risk as renal dysfunctions using glomerular filtration rate (GFR) of the general population in Korea in 2005.

Methods: The sample included 3,580 Korean men and women aged 20 years or older. Glomerular filtration rate (GFR) is a measure of kidney function. Normal renal function as defined as a GFR ≥ 90 mL/min/1.73m2, a GFR 60 to 89 mL/min/1.73m2, was considered mild renal dysfunction, a GFR of 30 to 59 mL/min/1.73m2 was considered moderate, a GFR of 15 to 29 mL/min/1.73 m2 was considered severe, and a GFR < 15 mL/min/1.73 m2 was considered renal failure. Subjects were classified into three groups based on their baseline GFR: greater than or equal to 90 mL/min/1.73m2 (normal group), 60 to 89 mL/min/1.73m2 (mild renal dysfunction), and less than 60 mL/min/1.73m2 (chronic kidney disease group). And 10-year cardiovascular risk was calculated based on Framingham score risk assessment.

Results: The distribution of renal function was 14.0%, 82.2%, and 3.8% in men, 4.0%, 85.5%, and 10.5% in women, respectively. For 10-Year risk in men, distribution of renal function was 2.07 (1.34), 2.25 (1.30), and 2.46 (1.29) , respectively (p<0.05). And for 10-Year risk in women, distribution of renal function was 1.04 (0.41), 1.13 (0.54), and 1.32 (0.55) , respectively (p<0.001). Conclusion: The study shows that cardiovascular risk based on Framingham score risk assessment increase as normal, mild renal dysfunction, and chronic kidney disease group in the community-based study for Korean adults men and women.

Learning Objectives:
To recognize cardiovascular risk based on Framingham score risk assessment as normal, mild renal dysfunction, and chronic kidney disease group.

Keywords: Chronic (CVD), Risk Assessment

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I'm a student at Graduate School of Public health, Seoul National University.
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.