Genomics in Public Health Practice: CDC-Funded Pilot Projects in Four State Health Departments

Integrating human genome-based information (e.g., genetic risk factors) and applications (e.g., family health history assessments) into public health research, policy, and programs could lead to new and better ways to prevent diseases and improve health in the United States. From 2003 to 2008, the Centers for Disease Control and Prevention funded state health departments in Michigan, Minnesota, Oregon, and Utah to provide leadership and establish capacity in genomics to support state-based chronic disease prevention and health promotion efforts. The states established partnerships with health care organizations, health plans, policy makers, academic and research institutions, and local public health agencies and organizations. Through these partnerships, the states integrated genomics into cancer control plans and family history assessments into disease prevention efforts for cancer, cardiovascular disease, and diabetes. They also helped educate health providers, public health practitioners, policy makers, and consumers. Through population-based surveys, the states gained knowledge about consumer awareness and use of family history in disease prevention and of direct-to-consumer genetic tests. In addition, the states developed standards for collecting and using family health history in health practice and contributed to the development of genetics-related state policies. The states successfully demonstrated genomics integration into disease prevention programs and core public health functions. These experiences provide important information to help guide future CDC plans and provides a resource for other state health departments and public health organizations to use.