203915 Healthy pregnancies: What do frogs and mice have to do with it?

Monday, November 9, 2009: 12:30 PM

Patrice Sutton, MPH , Program on Reproductive Health and the Environment, University of California San Francisco, Oakland, CA
Tracey J. Woodruff, PhD, MPH , Program on Reproductive Health and the Environment, UCSF, Oakland, CA
BACKGROUND: Should reproductive health providers, policy makers and the public act to prevent exposure to a chemical that causes male frogs to resemble females, makes mice unable to bear a healthy litter, and results in humans having a slightly elevated level of risk of spontaneous abortion? Weaving the scientific data into a coherent signal is a challenge that must be overcome if we are to take meaningful action to prevent harm. The University of California San Francisco Program on Reproductive Health and the Environment (PRHE) undertook a project, Navigating the Scientific Evidence to Improve Prevention, to develop a transparent methodology to efficiently vet, frame and synthesize the scientific evidence evaluating the environment and reproductive health that is consistent with preventing harmful exposures. METHODS: PRHE formed an interdisciplinary group of 20 scientists and advocates; conducted a literature review and compiled examples of existing efforts to inform the process; developed an outline of the relevant issues to be vetted, including but not limited to: the interpretation of data from animal, toxicological, pharmacological, human and ecosystem health studies, regulatory and other local, national and international government bodies, and the scientific basis for recommendations for prevention; and convened a meeting of collaborators. RESULTS: Results to date of this effort to provide reproductive health professionals with a guide to transforming emerging scientific discoveries about the role of the environment on reproductive health outcomes into healthy pregnancies, healthy children and the health of future generations will be presented.

Learning Objectives:
At the end of this presentations participants will: 1) Identify two reproductive health impacts related to exposure to chemicals in the environment; 2) Describe results to date of a collaborative process to develop a transparent and efficient methodology for vetting the relevant science; 3) Recognize the essential role of reproductive health clinicians in providing patients with prevention-oriented anticipatory guidance related to environmental exposures; and 4) List four ways that reproductive health providers can contribute beyond the clinical setting towards improved reproductive environmental health public policy aimed at primary prevention.

Keywords: Reproductive Health, Evidence Based Practice

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: Research Scientist with the UCSF Program on Reproductive Health and the Environment, spearheading the work to be presented
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.