210914 Human health concerns from bisphenol A: Review of the latest science

Monday, November 9, 2009: 1:30 PM

Kristina A. Thayer, PhD , National Toxicology Program (NTP), National Institute of Environmental Health Sciences (NIEHS), Durham, NC
Bisphenol A (BPA) has attracted a considerable amount of publicity over the past several years. For example, it was mentioned in Time Magazine's annual "Year in Medicine" list for 2008. BPA is a chemical produced in large quantities for use primarily in the production of polycarbonate plastics and epoxy resins. Polycarbonate plastics have many applications including use in some food and drink packaging, e.g., water and infant bottles. Epoxy resins are used as lacquers to coat metal products such as food cans and bottle tops. BPA can be detected in the urine of >90% of Americans and its presence in food and beverages is assumed to account for the majority of daily exposure in most people. BPA has proven to be a very controversial chemical because of the wide range of opinions held within the scientific community on the potential risk it poses for human health. In September 2008, the National Toxicology Program (NTP) released a report that identified evidence from experimental animal studies that raised "some concern" that current levels of exposure to human fetuses, infants, and children may result in developmental changes in the prostate gland and brain and diminish sexually dimorphic behaviors. The presenter discusses the findings that led to the NTP conclusion of “some concern” as well as new developments related to the regulation of BPA and identification of additional sources of exposure and other health effects of potential concern.

Learning Objectives:
Summarize the low dose effects of BPA Identify 3 specific sources of exposure to BPA and the most highly exposed population Discuss the scientific complexities and regulatory status of BPA

Keywords: Environmental Exposures, Children's Health

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I am a staff scientist at the NIEHS/NTP. I work on issues related to environmental exposures and their potential impacts on human reproductive and developmental health.
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.