211391 Evaluation of a novel preventative measure for the control of urinary schistosomiasis: A pilot intervention in Adasawase, Ghana

Monday, November 9, 2009: 5:30 PM

Karen Claire Kosinski, MSPH, BS , Civil and Environmental Engineering, Tufts University, Medford, MA
In Adasawase, Ghana, urinary schistosomiasis is caused by Schistosoma haematobium, a parasitic blood fluke transmitted through skin contact with excreta-contaminated water. Local schoolchildren contract schistosomiasis by playing, bathing, and washing clothes in a local river. Novel methods of primary prevention of schistosomiasis are being explored for use in this location. As part of a baseline survey of disease prevalence, schoolchildren aged 8 to 16 years (n = 247) submitted 4 urine samples for testing. 47 girls and 69 boys presented with eggs at least once. The majority of infected children in this population had mean egg counts lower than 50 eggs/10ml urine, but egg counts do not necessarily correspond to risk of morbidity or long-term sequelae. Only 5 of 247 children presented with both eggs and blood on all 4 test days, suggesting that accuracy in determining true infection status is improved by collecting and testing multiple urine samples. Of the 247 children tested 4 times for schistosomiasis, 234 (94.7%) were treated by Ghana Health Services with praziquantel during normal school hours. Local school heads and teachers communicated with parents regarding treatment, organized schoolchildren, and assisted with weighing children to ensure correct dosage. Treatment of all schoolchildren took place in June, 2008. Of the 116 schoolchildren who presented with eggs at least once, 105 were retested for schistosomiasis once in July 2008 to estimate treatment efficacy; 1 boy remained egg-positive. Program costs associated with urine testing and drug distribution will be reported.

Learning Objectives:
Design a primary prevention intervention for the control of schistosomiasis.

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I have an MSPH in parasitology and I am a PhD candidate in Civil and Environmental Engineering at Tufts University. I am the principal investigator of the work being presented.
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.