H1N1pandemic influenza transmission from humans to pets-Oregon 2009

There were a total of 4 ferrets and 2 cats confirmed with H1N1 in Oregon in 2009. All ferrets aged between 4-7 year presented with sneezing, coughing, lethargy and nasal discharge. Three of the ferrets had elevated temperatures of >103F (normal 101F-102.5F). None of the confirmed ferret cases had a previous history of health problems. Of the 2 cats affected with H1N1, aged 8 and 10 years, presented with severe respiratory distress, dyspnea and cyanosis but neither had an elevated temperature. One cat had a history if chronic respiratory infection. Nasal swabs and tissue samples collected in all cases and tested at Oregon State University, Veterinary Diagnostic Laboratory (OSU VDL). The samples tested positive by both the matrix and N1 rRT-PCR assays for the 2009 H1N1pandemic influenza virus. The USDA/APHIS/VS/National Veterinary Services Laboratories (NVSL) subsequently confirmed 2009 H1N1 pandemic influenza virus in the sample. Radiological studies in both cats revealed marked consolidation of the lung lobes and air bronchograms throughout the chest. In one case pleural effusion was identified. Histopathologic studies revealed bronchiolointerstitial pneumonia with epithelial necrosis and fibrin exudation in bronchioles and alveoli, were also present in both cats in this report. These are lesions typical for acute viral pneumonia.