220163 Chronic Kidney Disease and Metabolic Syndrome in Korean Adults between 1998 and 2007

Sunday, November 7, 2010

Shin Yi Jang , Graduate School of Public Health, Seoul National University, Seoul, South Korea
Shin Yi Jang , Division of Cardiology, Cariovascular Imaging Center, Cardiac and Vascular Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
Eun Young Ju , Department of Public Health, Graduate School of Public Health, Seoul National University, Seoul, South Korea
Duk-Kyung Kim , Division of Cardiology, Cariovascular Imaging Center, Cardiac and Vascular Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
Il-Ho Kim, PhD , Graduate School of Public Health, Seoul National University, Seoul, South Korea
Seung Wook Lee , Graduate School of Public Health, Seoul National University, Seoul, South Korea
Background The aim of this study is to examine the prevalence of chronic kidney disease (CKD) in metabolic syndrome (MS) and to investigate the association between MS and CKD after adjustment for socioeconomic position and health behavior factors in the general representative population in Korea in 1998 and 2007. Methods The sample included 9,170 Korean men and women aged 20 years or older. Subjects were classified into two groups based on their baseline glomerular filtration rate (GFR): 1) greater than or equal to 60 mL/min/1.73 m2 (non-CKD group; normal and mild renal dysfunction), and 2) less than 60 mL/min/1.73 m2 (CKD group; moderate, severe renal dysfunction, and renal failure). The MS was determined using National Cholesterol Education Program Adult Treatment Panel III criteria and the Asia-Pacific criteria for obesity based on waist circumference. Results The distribution of mild renal dysfunction was 57.0% and 78.0% in 1998 and 2007, respectively (p<0.001). And the distribution of CKD was 2.2% and 4.9%, respectively (p<0.001). The adjusted odds ratio for MS was 2.32 (95% Confidence Interval (CI) 1.58-3.417) and 2.91 (95% CI 1.55-5.47) after adjustment for confounders (age, gender, anemia, socioeconomic position, and health behavior factors) in 1998 and 2007, respectively. Conclusion This community-based random sample drawn from the entire Korean population showed that MS was significantly associated with CKD.

Learning Areas:
Biostatistics, economics
Chronic disease management and prevention
Epidemiology

Learning Objectives:
The aim of this study is to examine the prevalence of chronic kidney disease (CKD) in metabolic syndrome (MS) and to investigate the association between MS and CKD after adjustment for socioeconomic position and health behavior factors in the general representative population in Korea in 1998 and 2007.

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I have studied chronic epidemiology for 10 years in Hospital.
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.