Occupational Asthma due to Exposure to Epoxy Resins and Acid Anhydrides in Low Socioeconomic Status

Background Hexahydrophthalic anhydride (HHPA) is a low molecular weight organic acid extensively utilized in the manufacture of alkyd and epoxiresins; industrial applications include plastic reinforcement, adhesion, molding, and surface coating. HHPA exposure has, thus, been associated with haptenized autologous proteins and an array of immunologic respiratory conditions including asthma, rhinitis, epistaxis and nasal erosions. Method Team searched Pubmed and Medline with the terms “plastics”, “epoxy resins”, ”anhydrides”, “immunological conditions”,“asthma”, “low social status”, “low socioeconomic status”, and “workers” from 1960 to 2009 Results HHPA showed specific IgE antibody formation in exposed workers. Additional findings pointed out IgE-mediated respiratory sensitization due to HPPA exposure with clinical presentations of rhinitis, nasal mucosal erosions, epistaxis and serologic studies supportive of an immunologic mechanism. Bronchial reaction may be immediate, non-immediate, or both. Discussion It is vital to identify early exposure cases in order to improve chances of recovery and reduce risk of long-term adverse effects. A careful history, with particular attention to chemical processes at work, will usually alert the physician to the possibility of occupational asthma. Social and economic policies have a direct impact on the health and well-being of those who live and work under those policies. Conclusion A careful history, with particular attention to chemical processes at work, will usually alert the physician to the possibility of occupational asthma. Interventions and policies must address daily living conditions and issues related to low socioeconomic status, gender, racial disparities, availability of resources and access.