237085 Efficacy of HIV/AIDS Prevention Interventions in Asia, 1995-2009: A Meta-Analysis

Monday, October 31, 2011: 8:30 AM

Judy Y. Tan, PhD , Department of Medicine, University of California San Francisco, San Francisco, CA
Tania Huedo-Medina , Center for Health Intervention and Prevention, University of Connecticut, Storrs, CT
Michelle Warren, BA , Center for Health, Intervention, and Prevention, University of Connecticut, Storrs, CT
Michael P. Carey, PhD , Syracuse University, Center for Health and Behavior, Syracuse, NY
Blair T. Johnson, PhD , Department of Psychology, University of Connecticut, Storrs, CT
Background: The HIV/AIDS epidemic continues to grow in pockets across Asia, despite early successes at curtailing its spread in countries like Thailand. Recent evidence documents dramatic increases in incidence among risk groups and, alarmingly, the general population; such state of affairs calls for swift measures. This meta-analysis answers this call by summarizing the efficacy of sexual risk-reduction interventions for the prevention of HIV-infection in Asia. Method: Sexual risk-reduction outcomes (e.g., condom use, number of sexual partners, incident sexually transmitted infections, including HIV) from 46 behavioral intervention studies with a comparison condition and available by August 2010 were synthesized using meta-analysis. Analyses examined whether intervention effects varied as a function of hypothesized moderator variables. Results: Overall, behavioral interventions in Asia consistently reduced sexual risk outcomes. Condom use efficacy was stronger when interventions sampled more women, included motivational content, and did not include STI testing and treatment. Incident HIV/STI efficacy was stronger when interventions sampled more women, were conducted more recently, and included STI counseling and testing. Sexual frequency efficacy was stronger in interventions that were conducted in countries with lower human development capacities, with younger individuals, and included condom-skills training. Conclusions: Interventions for sexual risk-reduction interventions are efficacious; the magnitude of the effects covaries with specific intervention and structural components. The impact of structural factors on HIV intervention efficacy must be considered when implementing and evaluating behavioral interventions. Implications for HIV/AIDS intervention work, human development, and gender equity are discussed.

Learning Areas:
Planning of health education strategies, interventions, and programs
Public health or related public policy
Social and behavioral sciences

Learning Objectives:
1. Evaluate the efficacy of HIV prevention interventions in Asia using the first meta-analysis of HIV interventions conducted in Asia. 2. Identify characteristics of the population, intervention, and social structure related to HIV intervention efficacy in Asia. 3. Inform future HIV intervention design with respect to features of the population and socio-structural factors.

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I am the principal investigator of the work as presented.
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.