245318 HIV risk associated with injection drug use in Houston, Texas 2009: A Latent Class Analysis

Tuesday, November 1, 2011: 1:30 PM

Syed Noor, MSS, MA, MPH , School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX
Michael W. Ross, PhD , WHO Center for Health Promotion Research and Development, The University of Texas - Houston School of Public Health, Houston, TX
Dejian Lai, PhD , School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX
Jan Risser, PhD , Department of Epidemiology and Disease Control, University of Texas School of Public Health, Houston, TX
Background: Injection drug users (IDUs) are at increased risk of HIV infection because they are more likely to engage in high risk injection behaviors (e.g. needle sharing) as well as in high risk sexual behaviors (e.g. exchange sex). This analysis examines factors associated with HIV risk using a latent class approach.

Methods: Our study includes 523 eligible injection drug users, recruited into the 2009 National HIV Behavioral Surveillance project. Using maximum likelihood we calculated the posterior probability of being in an HIV risk class from 4 drug and 5 sexual behaviors separately. We simultaneously fitted separate logistic regression models to identify socio-demographic factors associated with HIV risk class.

Results: We identified 2 HIV drug risk classes: high (57%) and low risk (43%) and 2 sex risk classes: high (49%) and low risk (51%). Compared to the high HIV drug risk class, homeless IDUs (OR=0.34, 95% CI: 0.22-0.53) and IDUs who were arrested in past 12 months (OR=0.63, 95% CI: 0.41-0.95) had lower odds to be in low risk class. Regarding sexual risk, IDUs who visited a doctor in past 12 month had lower odds (OR=0.52, 95% CI: 0.32-0.83) to be in high risk class compared to low risk class.

Conclusions: Our results show that the majority of our IDUs were engaged in high HIV risk behaviors. Though temporality cannot be established due to the cross-sectional study design our findings indicate that homelessness and history of incarceration are associated with HIV risk.

Learning Areas:
Public health or related research
Social and behavioral sciences

Learning Objectives:
Learners will be able to •describe Latent Class Analysis approach to identify HIV risk classes based on observed drug and sexual risk behaviors. •list factors contextual to injection drug related HIV risk among a sample of injection drug users. •compare drug and sexual risk behaviors among high, and low HIV risk injection drug users.

Keywords: HIV Risk Behavior, Injection Drug Users

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I conceptualized and conducted this analysis
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.