246498 Polycystic Ovary Syndrome: Morbidity Issues and the Psychosocial Impact on Infertile Women

Monday, October 31, 2011

Audry Greenwell, PhD, RN, APRN , College of Nursing ETSU, East Tennessee State University, Burnsville, NC
Judy McCook, PhD, CNS, RN-BC , College of Nursing, East Tennessee State University, Johnson City, TN
Stacey Williams, PhD , Department of Psychology, East Tennessee State University, Johnson City, TN
Sheeba Anand, MD, MPH , James H Quillen College of Medicine, Internal Medicine PGY-1, East Tennessee State University, James H Quillen College of Medicine, Johnson City, TN
Beth Bailey, PhD , James H. Quillen College of Medicine, Family Medicine, East Tennessee State University, Johnson City, TN
Objective: Polycystic ovary syndrome (PCOS) is a multidimensional endocrine disorder and the leading female infertility. PCOS is characterized as a clustering of clinical concerns, which include hyperandrogenism, obesity, and menstrual abnormalities/infertility. These characteristics were examined with regard to their impact on women's psychosocial concerns and health related quality of life. Design: Cross-sectional, correlational Setting: Private endocrinology practice in the rural Southeastern U.S. Participants: The study sample consisted of 126 women with PCOS. Methods: Convenience sampling yielded 126 subjects who met the diagnosis for PCOS, underwent laboratory testing and physical assessment, completed psychological and quality of life survey instruments and were included in data analysis. Results: Results of multiple regression analyses, controlling for demographic covariates, were completed on markers of hyperandrogenism, obesity and current fertility intent. Findings revealed hirsutism was significantly related to increased symptoms of anxiety and somatization and decreased quality of life among women with PCOS, while elevated androgen levels were significantly related to decreased quality of life. Current fertility intent significantly impacted symptoms related to interpersonal sensitivity, anxiety, psychoticism, and the global symptom severity index. Specifically, women not currently trying to conceive had higher levels of these psychological symptom outcomes. Conclusion/Implications for nursing practice: Women with PCOS are at elevated risk for psychological distress, and psychological symptoms appear to increase with increasing severity of PCOS symptoms. Women not currently trying to conceive appear to be at higher risk for psychological distress and lower quality of life.

Learning Areas:
Chronic disease management and prevention
Social and behavioral sciences

Learning Objectives:
Identify which women with polycystic ovary syndrome (PCOS) may be at increased risk for psychological distress and impaired quality of life.

Keywords: Reproductive Health Research, Psychological Indicators

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I have worked with Dr. McCook for the pas six years as a nurse colleague and populations expert. I have been involved in subject recruitment, reviewed data analysis and helped determine which data to disseminate for posters, papers and manuscript development.
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.