251329 Significant Chagas Disease Transmission by a Previously Overlooked Vector

Monday, October 31, 2011: 3:30 PM

Karen Alroy , Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA
Christine Huang, MS , School of Medicine, University of Medicine and Dentistry of New Jersey, Newark, NJ
Victor Quispe-Machaca , Laboratorios de Investigación y Desarrollo, Universidad Peruana Cayetano Heredia, Lima, Peru
Jenny Annca-Juarez , Laboratorios de Investigación y Desarrollo, 3Universidad Peruana Cayetano Heredia, Lima, Peru
Cesar Naquira, MD , Laboratorios de Investigación y Desarrollo, Universidad Peruana Cayetano Heredia, Lima, Peru
Robert Gilman, MD, DTM&H , Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
Caryn Bern, MD, MPH , Centers for Disease Control and Prevention, Atlanta, GA
Michael Levy, PhD , Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA
We conducted a cross sectional serological and entomological survey for Chagas disease in four communities in Northern Peru. Human as well as domestic animal sera were tested for the presence of antibodies against Trypanosoma cruzi by ELISA and western blot, and intestinal contents of triatomines were examined for the parasite by microscopic analysis. A total of 529 people participated in the study, 108 dogs and 207 guinea pigs were sampled for blood, and 213 houses were searched for the triatomine vector. We found that 15.7% (83) of community members were seropositive for T. cruzi infection, as well as 13.8% (15) of dogs, and 3.3% (7) of guinea pigs. 39.9% (85) of households searched were infested with triatomine insects, and in 38.5 % of infested houses, at least one triatomine was found to be carrying T. cruzi. The sole species of triatomine vector encountered within the houses was Panstrongylus herreri, a species that was previously believed to be predominantly sylvatic. This is one of the first studies documenting extensive T. cruzi infection mediated by P. herreri.

Learning Areas:
Public health biology

Learning Objectives:
Describe a previously overlooked vector in the transmission of Chagas Disease

Keywords: Animals and Public Health, Zoonoses

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I am doing this as original research as part of my DVM MPH program
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.