251472 Use of buccal cells for genomic research: Lessons learned for the National Children's Study

Wednesday, November 2, 2011: 12:50 PM

Elaine M. Faustman, PhD DABT , Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA
One of the challenges for children's longitudinal cohort studies is the need for non-invasive biospecimen collection that can provide insight for multiple endpoints. This talk will discuss the use of buccal cells for both genetic and expression data and will furthermore explore the issue of feasibility, acceptability and cost to collect this kind of sample in a longitudinal cohort study. Optimization and characterization of within and between person variability will be discussed as well how such methods can be used to inform gene–environment questions. Dr. Faustman will draw upon her expertise as director of the Pacific Northwest Center of the National Children's Study and collaborator on multiple formative research efforts across the country. The Pacific Northwest Center for the National Children's Study includes a study location in Grant County, Washington, which is currently recruiting participants during the National Children's Study pilot phase using the Enhanced Household Based Recruitment strategy. In this protocol, listing of activities for identification of study eligible dwelling units is followed by residents receiving an advance mailed letter prior to household canvassing to determine recruitment eligibility. Starting in April, this site will move to Phase 2 where environmental and biological sample collection has been added. Dr. Faustman is an expert in toxicology, risk assessment, risk communication, and the translation of novel science for public health application. In additional to directing the Pacific Northwest Center for the National Children's Study, Dr. Faustman also directs the University's of Washington Center for Child Environmental Health Risks Research and the University of Washington's Pacific Northwest Center for Human Health and Ocean Studies.

Learning Areas:
Basic medical science applied in public health
Conduct evaluation related to programs, research, and other areas of practice
Implementation of health education strategies, interventions and programs
Planning of health education strategies, interventions, and programs
Public health or related research

Learning Objectives:
Discuss the application of buccal cells in non-invasive genomic research to inform the National Children’s Study.

Keywords: Child Health, Environmental Health

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I have decades of experience as an expert in maternal and child health. In additional to directing the Pacific Northwest Center for the National Children’s Study, I also direct the University’s of Washington Center for Child Environmental Health Risks Research at the University of Washington.
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.