251476 Building genomic capacity for the National Children's Study

Wednesday, November 2, 2011: 1:30 PM

James Swanson, PhD , School of Medicine, Child Development Center, University of California, Irvine, Irvine, CA
The extraordinarily rapid evolution of new genomic techniques and expansion of how they can inform longitudinal studies is breathtaking. The focus of this talk is to examine how such approaches may be used within the National Children's Study by utilizing the next generation of sequencing capabilities. Challenges of feasibility, scale, consent, and extrapolability will be highlighted in this discussion. Dr. Swanson directs the National Children's Study Vanguard Center for Orange County, California. The National Children's Study Vanguard Center for Orange County, California, one of the initial National Children's Study Vanguard locations, was established in 2005. It leads the implementation of the Study in Orange County, California. Dr. Swanson has assembled a team of NCS investigators from the University of California, Irvine (UCI); University of California, San Diego; University of Washington; University of Iowa; University of South Dakota; and Columbia University for this genome initiative. Dr. Swanson is Professor of Pediatrics and Director of the UCI Child Development Center, which is the home for several research and treatment programs for children with attention deficit hyperactivity disorder and other disorders of attention, behavior, and learning. Through his research, Dr. Swanson has developed procedures for monitoring the cognitive effect of stimulant medication, the most frequent treatment for this group of patients. His research also focuses on biochemical and genetic factors related to these disorders. Dr. Swanson is also investigating the effect of intensive, early intervention for children with attention and conduct disorders through a school-based treatment program.

Learning Areas:
Basic medical science applied in public health
Conduct evaluation related to programs, research, and other areas of practice
Environmental health sciences
Planning of health education strategies, interventions, and programs
Public health or related public policy

Learning Objectives:
Explain efforts underway to build genomic capacity for the National Children’s Study.

Keywords: Child Health, Environmental Health

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I am qualified to present because I have directed treatment programs for children with attention and behavioral problems, I am engaged in research on the prevention of those problems, and I am the principal investigator of a Vanguard Center of the National Children's Study.
Any relevant financial relationships? Yes

Name of Organization Clinical/Research Area Type of relationship
NIH National Children's Study Independent Contractor (contracted research and clinical trials)
Noven ADHA Medication Advisory Committee/Board
Johnson and Johnson ADHA Medication Consultant and Speaker's bureau and teaching engagements
Merck None Stock Ownership

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.