253056 Asthma risk in children of minority mothers who smoked during pregnancy: Did quit time matter?

Monday, October 31, 2011

Elizabeth Do, MPH (expected 2012) , Department of Epidemiology and Community Health, Virginia Commonwealth University, Richmond, VA
Hongjie Liu, MS, PhD , Department of Epidemiology and Community Health, Virginia Commonwealth University, Richmond, VA
Objectives: Maternal smoking cessation prior to pregnancy is associated with reduced risk of childhood asthma. Since it is unknown whether smoking cessation during pregnancy has similar effects, the objective of this study was to investigate whether the time of smoking cessation during pregnancy within minority mothers reduces childhood asthma. Methods: Data from the 2007-2008 National Health and Nutrition Examination Surveys (a stratified, multistage probability sample of the U.S. population) was analyzed using logistic regressions to investigate whether the exposure, time of maternal smoking cessation during pregnancy had an effect on the outcome, childhood asthma. Confounding variables included race, income, presence of other household smokers, and mother's age at birth. Results: Of US mothers, 1,979,896 smoked during pregnancy. Approximately 27% had asthmatic children. About 26% stopped smoking in their first trimester, 16% in the second, and 3% in the third. Compared to women who did not stop smoking during pregnancy, women who stopped in the first (OR = 0.27; 95% CI = 0.09, 0.76) and second (OR = 0.47; 95% CI = 0.15, 1.47) trimesters were more likely to have asthma-free children. However, these associations were only significant in the first trimester. Conclusion: The associations between the time of smoking cessation and asthma was only established in the first trimester, due to small sample size and missing data on mothers who quit smoking in the third. Future research is needed to examine the associations in large-scale studies. Keywords: maternal smoking, asthma, smoking cessation, pregnancy

Learning Areas:
Public health or related education
Public health or related research
Social and behavioral sciences

Learning Objectives:
Assess the effect that maternal smoking has on child asthma risk

Keywords: Maternal and Child Health, Tobacco

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I am an enrolled graduate student studying public health and a graduate research assistant for a NIH-funded study in maternal and child health.
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.