255802 Cost-effectiveness related to dose-response for chronic low back pain: Outcomes from a randomized controlled trial

Monday, October 29, 2012 : 2:45 PM - 3:00 PM

Darcy Vavrek, ND, MS , Center for Outcomes Studies, University of Western States, Portland, OR
Rajiv Sharma, PhD , Department of Economics, Portland State University, Portland, OR
Mitchell Haas, DC, MA , Center for Outcomes Studies, Western States Chiropractic College, Portland, OR
David Peterson, DC , Center for Outcomes Studies, University of Western States, Portland, OR
Background: Efficacy in relationship to dose of spinal manipulative therapy (SMT) for the treatment of chronic low back pain has been found and previously reported. This presentation will look at cost-effectiveness across dose of SMT.

Methods: We randomized 400 patients with chronic low back pain to receive one of four dose levels of care: 0, 6, 12, or 18 sessions of SMT from a chiropractor. All participants were scheduled for three visits per week for six weeks. Either the index intervention or light massage was rendered at each visit. The primary outcome was low back pain intensity. Economic analyses compare health care resources and costs for low back care, and assess the incremental costs to achieve a decrease in pain and disability scores.

Results: Effects across number of intervention visits and across intervention types will be presented using incremental cost-effectiveness ratios. Regression methods commonly used in production and cost theory to measure relationships between health care inputs, their costs, and participant outcomes, while controlling for other potential confounding variables. Analysis presented will include scheduled treatment visits, all low back-related healthcare resources used outside the study reported by the patients to estimate total costs, and cost-effectiveness analysis using the EuroQol EQ-5D to evaluate quality-adjusted life years (QALYs).

Conclusions: The first full-scale dose-response study of spinal manipulation has been successfully implemented. Cost-effectiveness analysis will be reported.

Learning Areas:
Biostatistics, economics
Clinical medicine applied in public health
Other professions or practice related to public health

Learning Objectives:
Discuss the relationship of cost-effectiveness analysis to dose-response of spinal manipulation for the care of low back pain. Compare spinal manipulation to a light massage control in a randomized controlled trial. Explain dose-response curves.

Keywords: Chiropractic, Cost-Effectiveness

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I am a co-investigator on this study
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.